急性低血压与前庭系统关系研究进展-中国科技论文在线.PDF

中国科技论文在线 急性低血压与前庭系统关系研究进展 # 1 2 2** 李成福 ，魏忠勋 ，李香兰 （1. 延边大学附属医院心脏大血管外科，延吉，133000； 5 2. 延边大学医学院,延吉,133000 ） 摘要：急性低血压可以兴奋外周前庭器官，并通过其传入神经到达前庭神经核进而影响孤束 核、延髓头端腹外侧区、脊髓灰质中间外侧柱以及肾上腺髓质参与血压的调控，其中有谷氨 酸的离子型受体参与。认为机体内可能存在由急性低血压诱发的外周前庭器官-前庭神经核- 10 孤束核-延髓头端腹外侧区-脊髓- 肾上腺髓质- 肾上腺素-去甲肾上腺素轴。 关键词：生理学，急性低血压；前庭系统；压力感受性反射； 中图分类号：R338.3 Research progression on the association of acute 15 hypotension and vestibular system 1 2 2 LI Chengfu , WEI Zhongxun , LI Xianglan ( 1. Department of Cardiothoracic Surgery，Affiliated Hospital of Yanbian University ，Yanji 133000; 2. Yanbian University College of Medic ine, Yanji 133000) 20 Abstract:Acute hypotension may influence the activity of the neurons in the MVN by the afferen t nerve from the peripheral vestibular organ. Vestibular system maybe participate in the process of blood regulation, and its central passageway may be vestibular apparatue -VN-NTS-RVLM-SP-Adrenal medulla, ionotropic receptor of glutamate may play an import ant role in this passageway. It is hypothesized that there may have vestibular apparatus -VN-NTS -RVLM -spinal cord-adrenal medulla 25 function axis induced by acute hypotension. Keywords : physiology; acute hypotension; vestibular system; baroreceptor reflex; 前庭器官位于内耳，是感知机体空间位置和运动状态的重要器官，由椭圆囊、球囊和三 个半规管构成。前庭器官受到刺激后通过前庭神经传达到前庭神经核（vestibular neucler, VN ） 30 后，诱