小儿人芽囊原虫感染53例分析.doc

PAGE PAGE 1 粪类圆线虫感染25例临床分析 胡缨1＊， 谢周华2，李艳文3 (1.广西医科大学第一附属医院检验科，广西南宁530021；2. 广西南宁市第四人民医院结核科三病区，广西南宁530023；3.广西医科大学寄生虫学教研室，广西南宁530021) 【摘要】目的： 探讨粪类圆线虫感染的临床特点及诊治方法。方法： 对近年我院收治的25例确诊为粪类圆线虫感染的临床资料进行回顾性分析。结果：大多患者有消化道和呼吸道症状：腹痛18 例，腹泻16例，咳嗽15例。患者标本中查见粪类圆线虫杆状蚴或丝状蚴。辅助检查中，66.00%患者血红蛋白降低，68.00%患者白细胞总数轻度升高，64.00%患者嗜酸性粒细胞升高，52.00%患者谷氨酰转移酶增高。经阿苯达唑治疗一疗程, 大多患者症状缓解，7天后重复一疗程，全部治愈，停药1周后复查均无复发，随访3个月亦无复发。结论：对于有土壤接触史且同时有消化道和呼吸道症状的病患,当常规治疗效果欠佳时，应考虑该虫感染的可能，配合使用离心沉淀法与碘液染色法是确诊简单有效的途径。阿苯达唑治疗效果良好。 【关键词】粪类圆线虫；感染；患者 Clinical Analysis of 25 Cases with strongyloides stercoralis Infection HU Ying1, Xie Zhou-hua 2, LU Zuo-chao3 (1.Department of Clinical Laboratory First Affiliated Hospital of Guangxi Medical University, Nanning 530021, China; 2 Third Ward, Fourth Peoples Hospital of Guangxi Nanning tuberculosis Branch; 3.Department of Parasitology, Guangxi Medical University) 【Abstract】Objective To investigate the clinical characteristics and approaches to diagnosis and treatment. Methods The clinical data of 25 cases admitted into our hospital in the recent years and confirmed as strongyloides stercoralis infection was retrospectively analyzed. Results Most of the patients presented alimentary and respiratory symptoms: abdominal pain (18 cases), diarrhea (16 cases), cough (15 cases). strongyloides stercoralis rhabditiform larvae or HYPERLINK app:ds:filariform%20larva \t _self ilariform larvae were found in the patients’ specimens. Decreased hemoglobin was detected in 66.00% of the group, elevation of white blood cells and eosinophilic granulocytes in 68.00% and 64.00% respectively, 52.00% infected patients’ level of glutamyl transferase (GGT) was elevated. Most of the patients’ symptoms were alleviated after one course of albendazole. All of the patients were cured after another course 7 days later. No recurrence happened one week after cease of medicine and during 3 months of follow-up. Conclusion Strongyloides stercoralis infection should be suspected when conventional therapy doesn’t