野菊花中黄酮类成分抗炎活性的虚拟筛选-药学研究.PDF

鑽鐮旂┒ 淼帮吉锝忥綍锝掞綆锝侊綄 锝忥絾 锛帮綀锝侊綊锝嶏絹锝冿絽锝曪綌锝夛絻锝侊綄锛诧絽锝擄絽锝侊綊锝冿綀 锛掞紣锛戯紭 锛讹綇锝?锛擄紬陰籍锝?锛戯紣 淼帮紩锛栵紩 淼 閲庤強鑺变腑榛勯叜绫绘垚鍒嗘姉鐐庢椿鎬х殑铏氭嫙绛涢€ 寮犻噾鏉瓣幀鍚曟枃鏂囮幀瀛欒繋涓滉幀姹鑺龟幀瀹嬪痉娴 (婊ㄥ窞鍖诲闄㈤檮灞炲尰闄㈥幀灞变笢婊ㄥ窞锛掞紩锛栵紪锛愶紦) 鎽樿:鐩殑銆€ 鍓嶆湡鐮旂┒鍙婃枃鐚姤閬撳潎琛ㄦ槑閲庤強鑺遍粍閰被鎴愬垎鏈夋槑鏄炬姉鐐庢椿鎬ш幀浣嗗叾鑽晥鐗╄川鍩虹鍜屼綔鐢ㄦ満鍒 灏氭湭鏄庣‘陰 璇ョ爺绌跺簲鐢ㄥ垎瀛愬鎺ユ妧鏈櫄鎷熺瓫閫夐噹鑿婅姳榛勯叜鎶楃値娲绘€х殑鑽晥鐗╄川陰 鏂规硶銆€ 鎼滈泦鐜板凡鍒嗙閴村畾鐨勶紦锛 锛 锛 涓噹鑿婅姳榛勯叜绫诲寲鍚堢墿缁勬垚閰嶄綋鏁版嵁搴撽幀閫夋嫨 锛┪猴饥 婵€閰 尾(锛╋极锛 尾)銆侊綈锛擄紭銆佺幆姘у悎閰 锛 (锛ｏ集锛 锛?銆佽偪鐦ゅ潖姝诲洜瀛 (锛达籍锛?绛夛紨 涓笌鎶楃値娲绘€у瘑鍒囩浉鍏崇殑闈剁偣缁勬垚鍙椾綋鏁版嵁搴撽幀搴旂敤锛わ綁锝擄絻锝忥綎锝咃綊锝 锛筹綌锝曪絼锝夛綇 锛?锛 (锛わ汲锛?锛?杞欢杩涜鍒嗗瓙瀵规帴陰 缁撴灉銆€ 閫氳繃鍒嗗瓙瀵规帴铏氭嫙绛涢€夑幀绛涢€夊嚭鎵撳垎鎬诲垎楂樹簬闃堝€肩殑榛勯叜绫诲寲鍚堢墿鍏 锛戯紤涓幃 缁撹銆€ 瀵规瘮鍒嗘瀽浜嗗師閰嶄綋涓 閲庤強鑺遍粍閰綔鐢ㄤ簬鍚勯澏鐐圭殑涓昏娲绘€т綅鐐龟幀鍒濇鎺ㄦ柇浜嗛噹鑿婅姳榛勯叜鎶楃値娲绘€х殑浣滅敤鏈哄埗陰负鐮斿彂鎶楃値鍒跺墏绫昏嵂鐗 鎻愪緵浜嗕竴瀹氱殑鍙傝€冴幃 鍏抽敭璇岤閲庤強鑺标幓榛勯叜陰绘姉鐐庢椿鎬ш幓鍒嗗瓙瀵规帴陰昏櫄鎷熺瓫閫 锛 锛 锛 涓浘鍒嗙被鍙耳锛诧紥锛橈紨銆€ 鏂囩尞鏍囪瘑鐮?锛°€€ 鏂囩珷缂栧彿:锛掞紣锛欙紩 锛曪紦锛楋紩(锛掞紣锛戯紭)锛戯紣 锛愶紩锛栵紩 锛愶紣锛 锝勶綇锝堹锛戯紣.锛戯紦锛曪紣锛? 锝?锝冿綆锝嬶綁.锝婏綈锝?锛掞紣锛戯紭.锛戯紣.锛愶紣锛 锛 锛讹綁锝掞綌锝曪絹锝 锝擄絻锝掞絽锝咃綆锝夛綆锝 锝忥絾 锝侊綆锝旓綁 锝夛綆锝嗭綄锝侊綅锝嶏絹锝旓綇锝掞綑 锝嗭綄锝侊綎锝忥綆锝忥綁锝勶綋 锝嗭綊锝忥綅 锛ｏ綀锝掞綑锝擄絹锝庯綌锝堬絽锝嶏綍锝 锝夛綆锝勶綁锝冿綍锝 锛? 锛猴绩锛★籍锛э吉锝夛綆锝婏綁锝呹幀锛脊锛 锛凤絽锝庯綏锝咃綆陰汲锛碉籍 锛癸綁锝庯絿锝勶綇锝庯絿陰挤锛★籍锛э鸡锝咃綆锝囷綉锝夛綆陰汲锛籍锛э激锝咃綀锝侊綁 (锛綁锝庯綒锝堬綇锝曪辑锝咃絼锝夛絻锝侊綄 锛碉綆锝夛綎锝咃綊锝擄綁锝旓綑 锛綇锝擄綈锝夛綌锝侊綄陰饥锝夛綆锝氾綀锝忥綍锛掞紩锛栵紪锛愶紦陰迹锝堬綁锝庯絹) 锛★絺锝擄綌锝掞絹锝冿綌:锛絺锝婏絽锝冿綌锝夛綎锝呫€€ 锛綇锝旓綀 锝愶綊锝咃綎锝夛綇锝曪綋 锝咃綐锝愶絽锝掞綁锝嶏絽锝庯綌锝侊綄 锝侊綆锝 锝岋綁锝旓絽锝掞絹锝旓綍锝掞絽 锝掞絽锝愶綇锝掞綌锝 锝擄綀锝忥綏锝咃絼 锝旓綀锝侊綌 锝嗭綄锝侊綎锝忥綆锝忥綁锝勶綋 锝嗭綊锝忥綅 锛ｏ綀锝掞綑锝擄絹锝庯綌锝堬絽锝嶏綍锝 锛 锝夛綆锝勶綁锝冿綍锝 锛?锝堬絹锝 锝忥絺锝栵綁锝忥綍锝 锝侊綆锝旓綁 锝夛綆锝嗭綄锝侊綅锝嶏絹锝旓綇锝掞綑 锝侊絻锝旓綁锝栵綁锝旓綑陰絺锝曪綌 锝旓綀锝 锝傦絹锝擄綁锝 锝侊綆锝 锝嶏絽锝冿綀锝侊綆锝夛綋锝 锝忥絾 锝夛綌锝 锝咃絾锝嗭絽锝冿綌锝夛綎锝 锝擄綍锝傦綋锝旓絹锝庯絻锝 锝楋絽锝掞絽 锝庯綇锝 锝冿綄锝咃絹锝?锛╋綆