患者血浆脑钠肽与心功能指标的相关性研究-心血管内科专业论文.docxVIP

山西 山西医科大学硕士学位论文 PAGE PAGE IV pg/ml）were higher than those in EH with DHF group（393.7±118.6 pg/ml，P＜0.05）, control group（14.5±10.9 pg/ml ，P＜0.05）, EH without HF group（36.0±20.1pg/ml P＜0.05）, three EH sub-groups without HF （ 24.5±14.1pg/ml ， P ＜ 0.05 ； 28.2±12.6pg/ml ， P ＜ 0.05 ； 49.0±21.4pg/ml，P＜0.05）.The plasma BNP levels in EH with DHF group（393.7±118.6 pg/ml） were higher than those in control group（14.5±10.9 pg/ml ，P＜0.05）, EH without HF group （36.0±20.1pg/ml P＜0.05）, three EH sub-groups without HF（24.5±14.1pg/ml，P＜0.05； 28.2±12.6pg/ml，P＜0.05；49.0±21.4pg/ml，P＜0.05）. LVEF、LVEDD、LAD and PtfV1 in EH with SHF group , there were significant differences comparing with DHF group, three EH sub-groups without HF, control group（P＜0.05）. With the worsening of HF ,the plasma BNP levels,LVEDD and LAD were increased,but LVEF and PtfV1 were decreased . （4）The plasma BNP level were negatively correlated with LVEF(r=- 0.826，P＜0．01), but positively correlated with LVEDD(r=0．829，P＜0．01).The plasma BNP levels were positively correlated with LAD(r=0．784，P＜0．01)，but negatively correlated with PtfV1(r=-0．754， P＜0．01)． Conclusions： Meanwhile the plasma BNP level，echocardiographic heart functional parameters and Ptf V1 are detected ， it will be obtained that heart damage degree, exact diagnosis of DHF and comprehensive assessment of left heart function in hypertensives． Key words： hypertension； B-type natriuretic peptide； left ventricular ejection fraction， left ventricular end diastolic diameter，left atrium diameter； P-wave terminal force-V1 PAGE PAGE V 中英文缩写词表 英文缩写 BNP 英文全名 B-type natriuretic peptide/Brain natriuretic peptide 中文全名 B 型利钠肽/脑钠肽 PtfV1 EH HF NYHA P-wave terminal force-V1 essential hypertension heart failure NewYork Heart Association V1 导联 P 波终末电势 原发性高血压 心力衰竭 纽约心脏病协会 DHF diastolic heart failure 舒张性心衰 SHF systolic heart failure 收缩性心衰 LVEDD 1eft ventricular end diastolic diameter 左室舒张末内径 LAD 1eft atrium diameter 左房内径 EF ejection fraction 射血分数 LVEF left ventricular ej