计算机辅助结肠镜图像诊断技术研究-生物医学工程专业论文.docxVIP

浙江大学研究生硕士学位论文摘 浙江大学研究生硕士学位论文 摘 要 ／ ／癌症在噩洲的高发率已引发了对用于癌症早期检测有效自动筛选方法的研 发的需要。目前，对结肠可疑恶性肿瘤进行诊断的计算机辅助分析技术还没有应 ＼ 用于临床，为此订／本课题的研究目的是提出一个基于多种信息融合的结肠镜图像 处理新技术，用于结肠镜图像的自动分析，进而进行癌症筛选。 针对彩色结肠镜图像，论文提出了一种融合颜色、亮度、空间距离和纹理信 息，采用随机聚类的彩色图像分割新算法。该算法采用分形维作为图像纹理特征 的度量，用一种基于元素间的相似性的随机聚类方法对特征空间进行聚类。该聚 类算法是基于对图中的切割进行采样的新的图论算法，可以自动获得最佳的类别 数目，该方法复杂度较低，而且其随机特性使得它具有抗噪声的鲁棒性。 在将结肠镜图像分类为正常和异常图像时，选用了误差反传训练的多层感知 器，结果显示这种网络神经元适合结肠镜图像分类。 ， 将本论文提出的方法应用到多幅结肠镜图像中 。劬步结果显示了论文所提出 的方法在结直肠图像的异常筛选上的可行性，有望为结直肠癌症的早期诊断提供 一种新的分析方法。一J ? 关键词：图像分割，分形维，、信息融合，随机聚类，BP神经网络，、多层感 知器 第3页 浙江大学研究生硕士学位论文 浙江大学研究生硕士学位论文 《计葬枫辅助结睡镜雷缘诊断技术研究》 ABSTRACT High incidence of cancer ca,∞s in Asia has triggered a need to develop an effective automated screening method for early detection．Currently computer-based colonoscopic diagnosis for suspected malignancies has not been employed．Themfore the objective ofthis dissertation is to develop a new technique for automated analysis ofthe colonoscopic images based on multi—information． Aiming at color colonoscopic images，a new algorithm for segmenting color colonscopic images by fusing multiple information，such as color,brightness，spatial distance and texture and then by stochastic clustering has been presented in this thesis． It makes the fraetal dimension(肋)as the measurement for texture feature in images and employs a stochastic clustering algorithm that uses pairwise similarity of elements．The clustering algnrithm，based on a new graph theoretical algorithm for the sampling of cuts in graphs，can obtain the optimal number of clusters automatically． The complexity of the algorithm is simpler,and its stochastic nature makes it robust against noise． A multilayer perceptron with backpropagation learning is selected for classifying colonoscopic images into normal and potentially abnormal categories．The results show that the neural network is more appropriate for the classification of colon Sta：tus． The new algorithm in this paper has been tested by a number of colonoscopic images．Initial results s