计算机视觉食管曲张静脉气囊测压技术的建立与临床应用研究-老年医学专业论文.docxVIP

因素，具有进一步开发应用的潜在价值。关键词 食管和胃静脉曲张 测压法 高血压,门静脉 食管曲张静脉出血 压力Computerized Endoscopic Balloon Manometry to Detect Esophageal Variceal Pressure:Experimental Validation and Clinical FeasibilityAbstractBackground and aimsVariceal pressure has been identified as the key factor leading to variceal rupture. Measuring variceal pressure is important in predicting esophageal variceal bleeding. Noninvasive balloon techniques assume that varices behave as an elastic structure because of their thin walls and lack of external tissue support; thus, the pressure needed to compress a varix (which can be sensed under direct vision using clear balloons) equals the pressure inside the varix. Manometry uses an endoscopic balloon to measure variceal pressure. Up until now, this method relied on the visual appearance of the varices and, therefore, was subjected to observer bias. Endoscopic balloon methods of measuring variceal pressure have not gained wide popularity. We have recently developed a computerized endoscopic balloon manometry (CEBM), with computer visualization to determine the moment of variceal wall collapse during balloon manometry instead of the visual evaluation of variceal compression used in the traditional balloon method. In this paper, we report the preliminary results of in-vitro and in-vivo testing of CEBM.The aims of the present study were: (1) to develop a new computerized endoscopic balloon manometry; (2) to validate this technique of CEBM in-vitro; (3) to test the clinical reliability and feasibility of this manometry by compared with the HVPG; and to correlate measured pressure values to endoscopic bleeding risk parameters as previously described; (4) to assess the applicability of this method for predict a first variceal hemorrhage in cirrhotic patients during the prospective study, and to detect clinical factors in the evaluation of the risk of bleeding.Patients and methodsThe CEBM system, comprising an esophageal variceal manometer and a computer, records variceal