无水酒精联合明胶海绵化学消融治疗肥厚型梗阻性心肌.pdfVIP

576 中国循环杂志 2018 年 6 月 第 33 卷 第 6 期（总第 240 期）Chinese Circulation Journal，June，2018，Vol. 33 No.6（Serial No.240） 临床研究 无水酒精联合明胶海绵化学消融治疗肥厚型梗阻性心肌病疗效分析 刘蓉，胡奉环，袁建松，高晓津，王娟，郭超，杨伟宪，乔树宾 摘要 目的：评价无水酒精联合明胶海绵化学消融治疗肥厚型梗阻性心肌病的安全性和有效性。 方法：分析 2017-05 至 2017-12 我院 7 例肥厚型梗阻性心肌病患者，行无水酒精联合明胶海绵化学消融的临床 资料。 结果：7 例患者中男性 5 例，女性 2 例，中位年龄 56（43~67）岁，最大室间隔厚度（19.6±4.8） mm，消融间隔 支 1~2 支，无水酒精用量为 1.4（1.0~2.0） ml，明胶海绵用量 0.5（0.1~1.3） ml，术后左心室流出道压差下降显著 [（31.6±12.6） mmHg vs （86.4±20.7） mmHg ， 1 mmHg=0.133 kPa，P 0.001）]，纽约心脏协会（NYHA）心功能分级 明显改善 [（1.4±0.5）级 vs （2.7±0.8）级 ， P 0.05]，无相关并发症。 结论：肥厚型梗阻性心肌病无水酒精联合明胶海绵化学消融安全、有效。 关键词 心肌病，肥厚型；化学消融；明胶海绵；无水酒精 Safety and Efficacy of Chemical Ablation With Anhydrous Alcohol Combined With Gelatin Sponge for Patients With Hypertrophic Obstructive Cardiomyopathy LIU Rong, HU Feng-huan, YUAN Jian-song, GAO Xiao-jin, WANG Juan, GUO chao ,YANG Wei-xian, QIAO Shu-bin. Coronary Heart Disease Center, National Center for Cardiovascular Diseases and Fuwai Hospital, CAMS and PUMC, Beijing (100037), China Co-corresponding Author: YANG Wei-xian, Email: wxyang2009@; QIAO Shu-bin, Email: qsbmail@ Abstract Objectives: To analyze the safety and efficacy of chemical ablation of anhydrous alcohol combined with gelatin sponge for patients with hypertrophic obstructive cardiomyopathy (HOCM). Methods: The clinical data of 7 HOCM patients, who underwent chemical ablation with anhydrous alcohol and gelatin sponge in Fuwai Hospital from May 2017 to December 2017, were analyzed. Results: There were 5 males and 2 females, with a median age of 56 years (range, 43-67 years), the mean interventricular septum thickness was (19.6 ± 4.8) mm, the number of ablated septal branch was 1-2, the amount of used anhydrous alcohol wa