天然药物有效成分的微波连续提取技术资料.docVIP

天然药物有效成分的微波连续提取技术 东南医药生物工程技术研究所 郭维图1 温州神华轻工机械有限公司 孙福平2 摘 要 ：天然药物有效成分提取长期以来一直采用水（醇）热回流提取和醇（水）沉，这种方法提取率低。为了加快中药提取的现代化进程，应用科技前沿技术，如超临界、超声波、微波浸提辅助技术及大孔径树脂、膜分离技术以及冷冻、喷雾和微波干燥相配套，组成一条技术先进又符合国情的生产线，这不啻是极为明智的选择。当前，中央把节约能源、降低消耗、减少污染立为基本国策；国家中医药局提出“中药新产品开发以高效、优质、安全、稳定为目标。”同时指出：“中药工业生产工艺和工程化技术落后，缺乏标准化的专用制药工业装备.”本文着重介绍一种在植物提取物研究、生产中应用的微波连续提取装置。通过22个产品其中单方14个反复8个近300次试验证实，采用微波连续提取工艺不但可以节能、降耗、减排，还可以使中药提取物生产实现自动化、连续化，同时使提取率和有效组分含量大幅度得到提高，进而使中药实现规模化、产业化。这是我们克服重重困难，身体力行执行中央指示和国家中医药局提出的中医药发展战略目标所获得的成果，以此向国庆60周年献礼。 关 键 词 天然药物 中药 提取 有效成分 传统提取 微波提取 微波功率 间歇 连续 节能 减排 降耗 新技术 装备 规模化 产业化 现代化 经济效益 Abstract Extracting effective ingredients of natural drugs always uses heat reflux extraction and alcohol-precipitation, these traditional extraction are inefficient. In order to accelerate Chinese tradition medicine extraction realizing modernization , it is a wise choice that uses the frontier science and technology composing of a production line which is advanced technological and in consonant with the situation of country, such as supercritical, ultrasonic, microwave extractioon assistive technology combined with large aperture Eastotac and membrane separation technique, refrigeration, spray and microwave drying. The central government put energy saving, lower consumption and pollution reduction as basic national policy. National bureau of TCM propose that ‘ New Chinese traditional medicine product development should take high efficiency, excellent quality, safty and steady as target’. At the same time, National bureau of TCM also point out that ‘ Chinese traditional medicine manufacturing technique is backward, and lack of standardized dedicated pharmaceuticals industry devices’. This article introduces a set of microwave extraction device used in plant extracts research and production. We used 22 kinds of medicine which contain 14 single and 8 compound medicine, for 300 times experiments to to verify that using microwave ectraction