黄芩提取液分离用CA纳滤膜的制备-生物化工专业毕业论文.docxVIP

ABSTRACTThe ABSTRACT The low level of separation technology led to a slow development of traditional Chinese medicine(TCM)modernization．The new NF membrane technology has its quality and environmental benefits superiority over traditional separation technology．Thus，the development of membrane materials wim hi曲flux and rejection and function at lower pressures are of great interest．In this paper,CA NF membrane was prepared from CA／solvent or CA／solvent／non—solvent system for separation of baicalin from radix SCntellariae raw extracts． First，for each CA／THF,CA／AC，CA／DIO system with different CA content，water flux and rejection of PEG400 were compared，the zero shear viscosities were obtained by falling ball viscometer,and effect of the exposed time to air on membrane behavior were compared． To gain stable behavior,non-solvent was added into CA／solvent system． The max water content for each binary system was tested by cloud point tirration，and the factors—water content and different exposed time—were investigated．The membranes surface and cross structures were taken by SEM． By intrinsic viscosity tests，the effects of solvent and non-solvent on dilute CA solution behavior were reflected．It was found that the properties of dilute solution affect the membrane performance．For binary system，the opposite relationship between viscosity slope coefficients(b)and water flux④ were due to solvent kind．For CA／solvent／non-solvent ternary system，[TI】 increased when 0中20．15．due to cooperative effect． The process(water extraction—centrifugal-UF-NF)was designed for separation bacailin，which made good separation results． Key words：Nanofiltration，CA，TCM，non—solvent，phase inversion II 第一章文献综述第一章文献综述 第一章文献综述 第一章文献综述 1．1膜分离技术文献综述 1．1．1膜分离技术发展简介 1748年，Abbe’Nollet发现水自发地透过猪膀胱渗透现象(Osmosis) 【”，标志着膜领域研究的开端。1907年，Beehhold成功制备出硝化纤维 素膜，并通过鼓泡实验标定了膜的孔径大d、[21。Elford，Zsigmondy和 Bachmann改进了Bcchhold的技术，由此，硝化纤维素微孔膜实现了商业 化。随后的20年，其他高分子物质特别是醋酸纤维素膜技术得到了极大 的研究和开发。二次世界大战以后，膜在饮用水安全方面的应用使膜研究 得到了美国军方的大力支持，发展更是迅猛。19