黄连紫草膏的工艺研究-药剂学专业毕业论文.docxVIP

1 材 料 与 仪 器 ······································································· 30 1.1 材料 ··············································································· 30 1.2 仪器 ·············································································· 30 2 实 验 内 容 和 方 法 ·································································· 30 2.1 提 取 液 的 处 理 ···································································· 30 2.2 高 效 液 相 色 谱 法 测 定 浓 缩 液 中 指 标 成 分 的 含 量 ···························· 30 第四部分 成 型 工 艺 考 察 ·························································· 33 1 材 料 与 仪 器 ······································································· 33 1.1 材料 ··············································································· 33 1.2 仪器 ·············································································· 33 2 单 因 素 筛 选 空 白 凝 胶 基 质 ······················································ 33 2.1 空 白 凝 胶 性 状 对 比 ······························································ 33 2.2 常 用 凝 胶 制 备 处 方 用 量 ························································ 34 2.3 不 同 比 例 凝 胶 基 质 与 药 物 结 合 的 稳 定 性 考 察 ······························· 34 3 正 交 试 验 优 选 凝 胶 配 方 ························································· 35 3.1 正 交 试 验 设 计 ···································································· 35 3.2 溶 出 方 法 及 条 件 的 拟 定 ························································ 35 3.3 高 效 液 相 色 谱 法 测 定 释 放 液 中 指 标 性 成 分 ································· 35 3.4 标 准 曲 线 的 制 备 ································································· 36 3.5 方 法 学 考 察 ······································································· 38 3.6 累 积 释 药 量 计 算 ································································· 41 3.7 释 药 曲 线 的 绘 制 ································································· 41 4 层 次 分 析 法 计 算 权 重 系 数 ······················································ 44 5 试 验 结 果 及