络病理论指导气虚血瘀型冠心病不稳定型心绞痛证治临床研究-中医内科学专业毕业论文.docxVIP

提 提 要 目的：本研究主要探讨了“络病”理论在冠-tl,病不稳定型心绞痛中的应用。方法： 参阅各种文献和总结临床观察病例，根据冠心病心绞痛中医病机及演变规律，确立了 以益气活血，搜风通络为主的治法。选择了51例冠心病不稳定型心绞痛病人，随机 分为2组，治疗组(26例)和对照组(25例)。两组均给以西药常规治疗，同时，治 疗组还给予益气活血，搜风通络中药汤剂，观察治疗前后两组症状及实验室指标变化。 结果：治疗组心绞痛缓解总有效率为92．31％，显效率为69．23％；心电图疗效总有效 率为80．77％，显效率为15．38％：中医症状改善总有效率76．92％，显效率30．77％， 与对照组比较有显著性差异(P0．05)。治疗组的血脂、血液流变学、心功能改善情 况优于对照组，且与治疗前比较有显著性差异(P0．05)。治疗后治疗组的内皮功能 指标ET、TXB2水平明显降低，NO水平升高，与治疗前及对照组比较有显著性差异 (P0．05)。结论：搜风通络法是对活血化瘀治法的深入，益气活血，搜风通络法是 中医药防治冠心病不稳定型心绞痛的新思路和新发展。 关键词；不稳定型·tl,绞痛；中药疗法；搜风通络法；内皮细胞 The The Study on Therapy of Unstable Angina by LUO Disease Theory Speciality：The study of Cardiovascular disease Author：Zhang Zhao Tutor：Gun Weixing ABSTRACT objective：To discussion of LUO Disease Theory application in therapy of unstable angina．Methods：Review literature and observe clinical cases to understand the disease and type of TCM which UA belongs to．establish treatment methods of soufengtongluo according to basic mechanic ofTCM；Fifty one patients ofcoronary heart disease(CHD) with unstable an酉na were divided randomly into treatment group(26 cases) and control group(25 cases)．Conventional western medical therapy was given to both groups．At the salTle time，the treatment group received herbal medicine，clinical symptoms and laboratory indexes in all the patients were observed before and after treatment．Results：In the treatment group，the total effective rate of relieving angina，improving ECG and meliorating symptoms were respectively 92．31％，80．77％and 76．92％；the corresponding control group rate were respectively 64．00％，48．00％，48．00％，which were significantly better than those of later,P0．05．The level of TC，TG and Fbg were decreased remarkably in the treatment group，which were statistically different compared with those of the control group，P0．05 or P0．01．The level of TXB2，ET,were decreased and the level of NO was increased remarkably after treatment，which were statistically different compared 、Ⅳitll those before treatment．Conclusion：The theory of LUO disease has