慢肾康治疗慢性肾炎气阴两虚型的临床研究-中医内科学专业毕业论文.docxVIP

提 提 要 慢’肾康是导师徐锡兰主任医师积数十年的I|伍床经验所创立的治疗慢性肾炎 气阴两虚证型的有效方剂。为了观察慢肾康的临床疗效，特展开本课题研究。 本研究采用单盲随机对照法，以慢肾康为治疗组、肾炎康复片为对照组。观 察两组病人治疗前后临床症状、肾功能、免疫功能、血液流变学、血脂、尿红细 胞、蛋白尿等变化。结果显示：慢肾康组总有效率为86．7％，肾炎康复片组有效 率为60％。两组疗效均进行统计学处理，差异有显著性意义(PO．01)。各项指 标的观察结果表明：慢肾康能够显著改善血液流变学、降低血脂、降低尿蛋白、 改善肾功能。能够改善神疲乏力、腰膝酸软、纳呆、浮肿等症状，增强机体免疫 力，减少感冒次数，远期疗效远胜于肾炎康复片组(PO．ol或PO．05)，长期服 用可以巩固疗效，治疗过程中未发现任何不良反应。 因此可以认为，慢肾康能通过健脾益肾，益气养阴，提高机体免疫功能，降 低血脂改善血液流变学，从而保护肾功能。 关键词慢性肾炎：慢肾康；临床研究 来经作肴、导坤阃麓 ■全文公希 Clinical Clinical Investigation of ManShenKangin Treating Chronic Glomerulonephritis Speciality：Clinical Research with Traditional Chinese Tutor：Prof Xu Xilan Author：Zang Zhiping Abstract ManShenKang(MSK)is an effective prescription in treating deficiency of qi and yin of chronic glomerulonephritis(CGN)which is invented by Prof．Xu Xilan on the basis of experience for several decades years．To further investigate its clinical observation，this dissertation conducts clinical observation．Single—blind，randomized controls are adopted．MSK is treating group and healing tablet of kidney inflammation(HTKI)is control group．Observing the change of clinical symptoms， kidney function，immunity function，blood rheology,lipid metabolism and proteinuria in two groups The clinical observation demonstrates that MSK s effective quotiety is 86．7 percent while HTKI is 60 percent．MSK carl clearly improve clinical symptoms． clearly reduce the urine protein，reduce BUN and Scr,improve lipid metabolism and blood viscosity,its effectiveness is better than that ofcontrol group(PO．01 or P0 05) It can consolidate the effect and improve the ability of resisting diseases if take it for long time． Therefore，MSK can stabilize kidney function by strengthening spleen and kidney,Increasing qi and yin，improving irmnunity function，improving lipid metabolism and blood viscosity， Key Word Chronic glomerulonephritis；ManSenKang；Clinical investigation． 原创性声明本人郑重声明：所呈交的学位论文，是在导师的指导下独立完成 原创性声明 本人郑重声明：所呈交的学位论文，是在导师的指导下独立完成 的，文中除注明引用的内容外，不包含任何其他已经发表的科研成果。 对本文研究做出重要贡献者，已在文中以明确方