上海交通大学耳鼻咽喉科学英文版课件 Meniere’s Disease.pptVIP

Intratympanic Steroids Author Med Protocol Pts A AB Other Sennaroglu Dex 1mg/ml QoD x 3 mon 24 41% 72% No change in tinnitus or HL Hirvonen Dex 16mg/ml 3 doses in 1 wk 17 76% No change in tinnitus or HL Barrs Dex 4mg/ml 2x/wk x 1mon 21 52% 3 month data 43% 6 month data Barrs Dex 10mg/ml Qwk x 4-6 wks 34 32% 2 year data Arriaga Dex 8mg/ml IT gelfoam x 1 15 No improvement in hearing Silverstein Dex 8mg/ml Qd x 3 days 20 No improvement in hearing or tinnitus Intratympanic Ablation Fowler (1948) and Schuknecht (1957) established role of aminoglycoside therapy. Streptomicin used initially Vertigo e