西安市533例3～18岁儿童血清维生素D水平分析.docVIP

西安市533例3?18岁儿童血清维生素 D水平分析 史晓薇刘黎明帖利军 西安交通大学第一附属医院 摘要： 目的了解西安市§8儿童维生素D[25 (OH) VitD,简称VitD]的营养状况及影 响因素。方法选择2015年7月到2017年2月期间的寒、暑假在西安交通大学 第一附属医院儿保科做健康体检的533例3J8岁西安市儿童为研究对象，采用酶 联免疫吸附法(ELISA)检测其血清VitD水平，并分析季节和性别的影响;进一 步按照被研究儿童所处学校的性质，将其分为幼儿园组，小学组和中学组，比 较三组儿童VitD的营养状况。结果 儿童血清VitD水平为24. 94±1.03ng/mL, VitD缺乏和不足的检出率分别为34. 71% (185/533)和34. 15% (182/533)。寒 假与暑假儿童 VitD 水平(21.20±11.01ng/mL vs 27. 71 ±8. 68ng/mL, t=7. 62, P0. 001)及不同VitD水平的检出率差异均有统计学意义(57. 71%vs 17. 64%, x2=93. 13, P0. 001) o 男童与女童 VitD 水平(25. 06±10. 67ng/mL vs 24. 72±9. 52ng/mL, t=0. 38, P0. 05)及 VitD 缺乏检出率(35. 03%vs 34. 17%, x 2=0. 04, P0. 05)差异均无统计学意义。幼儿园组、小学组和中学组VitD水 平分别为 31. 93±10. 02ng/mL 22. 33±8. 34ng/mL 和 19. 45±7? 27ng/mL (各组 间比较t值分别为10.56、10. 49和2.19,均P0. 05),且三组儿童不同水平 VitD的检出率差异存在统计学意义(x $二125.82, P0. 05)。结论 西安市3$ 岁儿童VitD缺乏率较高，尤其是屮、小学阶段的儿童更为突出，医务人员应重 视对该部分儿童VitD营养的保健指导。 关键词： 维生素D水平;318岁儿童;影响因素;酶联免疫吸附法; 作者简介：史晓薇(1971—),女，副主任医师，博士，主要从事儿童保健的研 究。 收稿日期:2017-05-11 基金：国家自然科学基金资助项目(No. Serum vitamin D levels in 533 children aged 3-18 years in Xian SHI Xiao-wei LIU Li-ming TIE Li-jun First Aff订iated Hospitol of Xian Jiaotong University; Abstract： Objective To investigate the nutritional status and influencing factors of vit am in D[ (25 (OH) VitD, referred as VitD] in childre n aged 3-18 years in Xi an. Methods A total of 533 chi ldren aged 3T8 years old, who took physical examination in summer and winter Vcication in First Affilieited Hospital of Xi an Jiaotong University, were selected during July 2015 to Februar)^ 2017. Enzyme-linked immunosorbent assay (ELISA) was used to detect the levels of VitD in serum and the influence of season and gender was analyzed. The children were further divided into kindergarten group, primary school group and middle school group according to the nature of school they studied in to compare the VitD nutritional status among groups. Results The serum VitD level of the studied children was 24. 94± 1. 03 ng/mL, and the detection rates of VitD deficiency and insufficie