上海交通大学妇产科学03级七年制课件十二 Polycystic Ovary Syndrome.pptVIP

2006-12-6 PCOS Polycystic Ovary Syndrome Introduction Definition: polycystic ovary syndrome (PCOS) is a generic description for a broad spectrum of clinical and morphological findings in women with an endocrine dysfunction, specifically abnormal androgen production and metabolism. PCOS was first identified by Stein and Leventhal in 1935 so that it can also be known as Stein – Leventhal Syndrome. Etiology Pathopysiology “Vicious cycle” Abnormal gonadotropin secretion Excess LH and low, tonic FSH Hypersecretion of androgens Disrupts follicle maturation Substrate for peripheral aromatization