慢性心力衰竭患者血清醛固酮水平与中医病理要素“瘀”“水”的相关性研究-中西结合临床专业毕业论文.docxVIP

慢性心力衰竭患者血清醛固酮水平与中医病理要素“瘀” “水”的相关性研究 中 文 摘 要 目的： 探讨慢性心力衰竭患者血清醛固酮水平与中医病理要素 “瘀”“水”的相关性，为慢性心力衰竭中医辩证提供客观化的依据，从 而更好的指导临床辩证及治疗慢性心力衰竭。 方法： 收集 150 例慢性心力衰竭患者的四诊资料，抽血检测血清 醛固酮水平，采用 2*2 析因分析，探讨血清醛固酮水平与慢性心力衰竭 患者中医病理要素“瘀”“水”是否具有相关性，指导临床对于慢性心力 衰竭的辨证论治。 结果： （１）将病例分为有“瘀”、无“瘀”组时，醛固酮水平有 “瘀”高于无“瘀”患者，但组间 P＞0.05，无统计学差异。（２）将病 例分为有“水”、无“水”组时，醛固酮水平有“水”组高于无“水”患 者，且存在非常显著的统计学差异（P＜0.01）。（３）将病例按瘀，水性 质不同分为 4 组：瘀血组、水停组、瘀血水停组、非瘀非水组，醛固酮 水平水停组＞瘀血水停组＞瘀血组＞非瘀非水组，且各组之间比较有非 常显著的统计学差异（P＜0.01），水停组与瘀血水停组、瘀血组、非瘀非 水组之间两两比较均有非常显著的统计学差异 P＜0.01，瘀血水停组、瘀 血组、非瘀非水组之间两两比较差异无统计学意义 P＞0.05。（４）以醛 固酮为应变量，水停积分为自变量作直线回归时发现醛固酮水平与水停 积分存在线性相关。 结论： 慢性心力衰竭患者血清醛固酮水平与中医病理因素瘀、水 密切相关，且其相关性水停＞瘀血。且醛固酮水平与水停症候积分呈线 性正相关。说明醛固酮水平与慢性心力衰竭致病中医病理因素中属瘀、 水密切相关，且其相关性水停＞瘀血。即可认为水停症候积分越高，醛 固酮水平越高。故可作为慢性心力衰竭水停的客观化辨证依据。 关键词： 慢性心力衰竭，醛固酮，病理要素，证素辩证，症候积分 Chronic heart failure patients serum aldosterone l- evel and TCM pathological factors stasis and water related research ABSTRACT Objective: To investigate the blood of patients with chronic heart failure aldosterone level and pathological factors Stasis and water relationship, The objective basis is provided for chronic heart failure TCM dialectical. In order to better guide clinical dialectical and treatme nt of chronic heart failure. Method: Collecting diagnostic data of 150 cases of patients with chronic heart failure, Detection of serum aldosterone level, Using 2*2 f- actorial analysis, serum aldosterone levels in patients with chronic heart failure TCM pathological factors stasis and water is the correlation, To guide the clinical diagnosis and treatment of chronic heart failure in. Result: (1) The patients were divided into the Yu, no stasis g- roup, Aldosterone levels are stasis higher than that without stasis p- atients, But between group P 0.05, no significant difference. (2) The patients were divided into the water, free water group, Aldosterone levels are water group was higher than that of no water pat