脉冲组织多普勒技术对正常人及高血压病患者心功能的再评价-影像医学与核医学专业毕业论文.docxVIP

华 华 中 科 技 大 学 硕 士 学 位 论 文 PAGE 3 PAGE 3 间隔、后壁、前壁、下壁相比，明显降低；高血压患者舒张功能 E/A 比值及后间隔 Ve/Va 比值、前间隔 Ve/Va 比值、后壁 Ve/Va 比值、前壁 Ve/Va 比值、下壁 Ve/Va 比值与正 常对照组相比，明显减低(P＜0.05)；③高血压患者肥厚组和非肥厚组的室壁舒缩功 能相比没有明显统计学意义(P 0.05)；④左室侧壁及右室游离壁的峰值速度与正常 对照组相比没有明显统计学意义（P 0.05）； ⑤瓣环不同部位的心肌收缩及舒张的 幅度不同(P0.05)； 结论 ①脉冲组织多普勒技术所测正常人在瓣环不同部位的收缩期峰值速度及 Ve/Va 比值不一致； ②与正常人相比，高血压病患者瓣环处不同部位收缩期峰值速度 及 Ve/Va 比值减低，但在不同部位减低程度不一致，提示心脏室壁不同部位对高血压 的反应不一致，其机理有待进一步研究。 [关键词] 组织多普勒； 高血压； 室壁运动； 心脏功能 Re-evaluation of heart function By pulsed tissue Doppler imaging in patients with hypertension and healthy subjects Postgraduate candidate: Wang Yubo Tutor : prof. Deng Youbin Abstract Objective To explore the PW-TDI for evaluating left ventricular function of normal and essential hypertension patients. Methods 43 patients with essential hypertension including 22 cases with hypertrophy and 21 cases with non-hypertrophy were selected. 65patients were randomly enrolled as normal control group. Measure myocardial motion peak velocity Vs，Ve, Va and calculate the Ve / Va ratio on valve annulus of left ventricular posterior septum ,lateral wall, right ventricular free wall, anterior wall,inferior wall,anterior septum and,posterior wall at standard long-axis view, 2-chamber view and 4-chamber view of left ventricular with TDI.Measure left ventricular ejection fraction (LVEF)with two-dimensional echocardiography、diastolic peak E, peak A on mitral valve with conventional pulsed Doppler ultrasound and calculate the E / A value. Results ①Compared with controls，the systolic peak velocity on posterior septum、anterior septum、posterior wall、anterior wall、inferior wall of hypertensive patients were lower (P 0.05) . ②The diastolic peak velocity on posterior septum 、anterior septum 、posterior wall、 anterior wall、inferior wall of hypertensive patients were lower than the controls .the diastolic E / A ratio and Ve / Va ratio on posterior septum 、anterior septum 、posterior wall、anterior wall、inferior wall were significantly lower than th