离子液体提取猪骨羟基磷灰石工艺-化学工程专业毕业论文.docxVIP

关键词：羟基磷灰石；离子液体；猪骨；提取 关键词：羟基磷灰石；离子液体；猪骨；提取 万方数据 ABSTRACTHydroxyapatite(HAP)is ABSTRACT Hydroxyapatite(HAP)is the main inorganic component of natural bone tissue．It is regarded as bone repair replacement material with the laJIgh performance because of possessing biocompatibility and bone conduction effect．The major products are made by artificial synthesis．There are some differences with human hydroxyapatite on the structure performance．The products from natural pig bones are more close to human body．Ionic liquids have good solubility，non—toxic harmless and environment protecting．Hydroxyapatite Was extracted from pig bones which were dissolved directly by the ionic liquids．It embodies the effective utilization of renewable resources． Hydroxyapatite Was synthesized by chemical precipitation method， using Ca(N03)2·4H20 and(NH4)2HP04 as raw materials．The yield of hydroxyapatite was used as the experiment target．The better result was showed by orthogonal experiments： n(Ca)／n(P)21．67，reaction temperature 40。C，(NH4)2HP04 dropping speed 1．0 mL／min。pH 9～10，concentration ofCa(N03)2·4H20 and(NH4)2HP04 0．15 mol／L，assembly time 24 h． The yield of hydroxyapatite was around 84．6％under the better condition．Fourier transform infrared(rTm)，X—ray diffraction(XRD)and scanning electron microscopy(SEM)were applied for the analysis ofthe product． The bromo--1--ethyl-·3-methyl-·infidazolium ionic liquids([EMIM]Br)dissolved the pig bones．Dissolution temperature，mass ratio of pig bones and[EMIM]Br and dissolution time were investigated．Exploring by single factor experiments range of process parameters，the main parameters were used for the orthogonal experiments．The better process conditions were dissolution temperature 220℃，mass ratio of pig bones and[EMIM]Br 1：30，and dissolution time 50 min．The ration of dissolved pig pones was around 68％under the better condition． Hot stage polarized optical microscopy(POM)was used to observe the dissolution process ofpig bones in[EMIM]Br． Pig bones wer