分子伴侣参与调控动植物的发育和进化进程-遗传.PDF

HEREDITAS (Beijing) 2010 5 , 32(5): 443―447 ISSN 0253-9772 综述 DOI: 10.3724/SP.J.1005.2010.00443 分子伴侣参与调控动、植物的发育和进化进程 陈建南 , 100101 近年来, 人们对分子伴侣的功能研究取得了很大进展, 阐明了它参与细胞新合成蛋白多肽的折叠、组装、 运输和蛋白质的降解过程。在这些过程中, 伴随着分子伴侣表达量的高低变化, 细胞线粒体数量也会发生相应 的变化。文章综述了分子伴侣参与调控动、植物的发育和进化进程, 如: 动、植物育性调控, 抗逆境能力提高 及热休克蛋白— 多肽复合物的肿瘤免疫治疗探索等。 分子伴侣; 热休克蛋白; 雄性不育; 肿瘤免疫 Progress in molecular chaperones participating in regulations of plant and animal development and evolution CHEN Jian-Nan Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing 100101, China Abstract: Progresses have been made on the functions of molecular chaperone in folding, assemble, and transportation of the proteins synthesized in novo and the degradation of proteins. The number of midochondria was changed in combination with the change of the expression of chaperone. Here, we would elucidate the progress in chaperone participating in regula- tions of plant and animal development and evolution. This review mainly focused on the regulation of plant and animal fertility, the improvement of stress resistance, and some progresses in tumor treatment of heat shock protein. Keywords: molecular chaperon; heat shock protein; male sterility; tumor immunity (Heat shock proteins, HSPs) [4~6] , : HSP70 N ATPase C HSP110, HSP100, HSP90, HSP80, HSP70, HSP60, , N ATPase HSP40 HSPs, , ATP , C (Molecular chaperone), HSP70[1~3] , HSP70 HSP70 , HSP70 12 , HSP70 , , HSP70 , , , (HSP70)(Heat shock cognate, HSC70), , ,