临床病例研究报告多个牙先天缺失患者的修复方法及评价-口腔修复学专业论文.docxVIP

V V 英文摘要 [Abstract] Objective: The aim of this study was to evaluate the effect of different prosthodontic treatment using in patients with hypodontia. Methods: The patients with hypodontia were given different prosthodontic treatment according to patients’ oral situation, age and subjective will, such as fixed partial dentures, removable partial denture, and complete denture. Prostheses were analyzed from the aspects of retention, masticatory function and periodontium of residual tooth, temporal-mandibular joint and the facial bones were evaluated from CBCT 6-month later. Result: All patients and their parents were satisfied with the improvement on facial esthetics and retention when their treatment completed. After 6-month follow-up, all patients presented significant improvement in oral function and psychosocial activi- ties. The prostheses exhibit good retention and stability, CBCT showed that the peri- odontium of residual tooth had no lesion, and the mandible and maxilla were being developed. Conclusion: For the restorations of patients with hypodontia, the ideal treatment needs the cooperation of orthodontics, prosthodontics and implantology. We find that the conventional prosthodontic treatment such as fixed partial dentures, removable partial denture, and complete denture also can achieve desired results. Key words: hypodontia; conventional prosthodontic treatment；CBCT 病例报 病例报告 PAGE PAGE 10 第1章. 正文 前言 1. 先天缺牙的分型 先天性的恒牙缺失是口腔科医生在临床工作中经常遇到的问题之一。最常 见的是个别恒牙的缺失，如第三磨牙、第二双尖牙和上颌侧切牙[1]。先天缺牙 根据是否有伴发症状可分为：①单纯性或非综合征型先天缺牙，即仅有牙齿的 先天缺失；②综合征型先天缺牙，即先天缺牙同时伴有其他器官的发育异常。 与 先 天 缺 牙 相 关 的 综 合 征 和 系 统 疾 病 主 要 包 括 ： 外 胚 叶 发 育 不 全 综 合 征 （ectodermal dysplasia，ED）、唇腭裂、Vander Woude 综合征、Down 综合征、 Wolf-Hirschhorn 综合征、Kallmann 综合征、Rieger 综合征、Johansson-Blizzard 综合征等。根据缺牙数目可分为个别牙缺失，多个牙缺失和先天性无牙。多个 牙缺失是指缺牙数目在 6 个及 6 个以上者（不包括第三磨牙）[2]。 2. 先天缺牙的病因 大量研究证实，先天缺牙与环境因素及遗传因素有关。在先天缺牙患者的 一级亲属中，先天缺牙的患病率（22%）远高于普通人群（44%）[3]。对双生子 的研究也证实了先天缺牙有着明显的遗传倾向，同卵双生子先天缺牙的遗传度 明显高于异卵双生子[4]。目前已经明确的与单纯性缺牙有关的基因有 MSX1