利用噬菌体展示技术鉴定猪瘟病毒E2蛋白抗原表位-预防兽医学专业论文.docxVIP

AbstractClassical Abstract Classical swine fever(csF)，one ofOIE Listed diseases。is oaused by Classical swinefever virus (cSFV)．CSF is hi【ghly contagious fatal disease in pigs with mortality around 80％to 90％，and it is epidemicorendemicworldwide(notincludingNorthAmericaandOceania)． Epitopes，or antigenic determinants，are antigen domains with affinity to antibody．Epitopes play very important role in the structure and function ofprotein antigens．Precise epitope mapping may help design more reasonable vaccines and diagnostic reagents．To facilitate understanding the structure and function of CSFV E2