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设计将基层医疗精神疾病评估工具中及翻译成中文在所普通科医务所由位候诊病人填写问卷另外医生在不知结果的情况下对病人采用项问题中文版汉米尔顿抑郁表评估以此作为诊断抑郁症的标准再为及结果验证其有效性主要测量内容及的灵敏度及特异度及之间的皮尔逊相关性结果灵敏度为特异度为当分界点为灵敏度为特异度为及之间皮尔逊相关性为问卷在过去的一个月您曾否经常被以下事情烦扰是否几乎没有兴趣去做事感觉情绪低落抑郁或绝望问卷表一填写问卷病人性别与年龄表二灵敏度及特异度灵敏度特异度表三灵敏度及特异度灵敏度当分界点为特异度图一及
设计 --- 将《基层医疗精神疾病评估工具(PRIME-MD)》中2Q及PHQ-9 翻译成中文。 在 14 所普通科医务所,由357位候诊病人填写问卷。 Design --- The 2Q and the PHQ-9 questionnaires from the Primary Care Evaluation of Mental Disorders Procedure (PRIME-MD) were translated into Chinese. 357 Patients from 14 general practice clinic in Hong Kong were asked to fill in the questionnaires before they saw their doctors. 另外医生在不知结果的情况下,对病人采用 17 项问题中文版汉米尔顿抑郁表(CHDS) 评估,以此作为诊断抑郁症的标准,再为2Q及PHQ-9结果验证其有效性。 The general practitioners, blind to the results, then applied the 17 items Chinese Hamilton Depression Rating Scale (CHDS) for the patients. The 2Q and the PHQ-9 were then validated against the CHDS, which served as the gold standard for depression detection. 主要测量内容 2Q及PHQ-9 的灵敏度及特异度 PHQ-9及CHDS之间的皮尔逊相关性(Pearson Correlation)。 Main outcome measures Sensitivity and specificity of the 2Q and PHQ-9 Pearson Correlation between the PHQ-9 and CHDS 结果 2Q灵敏度为96.7%,特异度为73.4%。 PHQ-9 (当分界点为9) 灵敏度为 80%,特异度为92%。 PHQ-9及CHDS 之间皮尔逊相关性为0.793 (p0.01)。 Results Sensitivity and specificity of the 2Q were 96.7% and 73.4% respectively. Sensitivity and specificity of the PHQ-9 at cut-off point of 9 were 80% and 92% respectively. Pearson Correlation between the PHQ-9 and the CHDS was 0.793 (p0.01). 2Q问卷 在过去的一个月,您曾否经常被以下事情烦扰: 是 否 几乎没有兴趣去做事 □ □ 感觉情绪低落、抑郁或绝望 □ □ PHQ-9 问卷 表一:填写问卷病人性别与年龄Table 1: Subject Characteristics: Sex Age Male Female Total Age Mean SD N Mean SD N Mean SD N 40.96 13.100 134 40.57 13.451 212 40.89 13.294 357 表二:2Q 灵敏度及特异度Table 2: Sensitivity and Specificity of 2Q 灵敏度=96.7% 特异度=73.4% Sensibility=96.7% Specificity=73.4% CHDS ≦ 16 CHDS 16 Total 2Q = 0 240 1 241 2Q 0 87 29 116 Total 327 30 357 表三: PHQ-9 灵敏度及特异度Table 3: Sensitivity and Specificity of PHQ-9 灵敏度(当分界点为9)=80% 特异度=92% Sensibility (cut-off point=9)=80% Specificity=92% CHDS ≦ 16 CHDS 16 Total PHQ-9≦9 301 6 307 PHQ-9 9 26 24 50 Total 327 30 357 图一:CHDS及 PHQ-9 相互关系 Graph 1: Correlation between CHDS and PHQ-9 CHDS 及 PHQ-9 相互关系
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