心力衰竭的同步化治疗CRT CRT-D.ppt

* LVEF越低，心脏骤停发生率越高。 * 在多个临床研究中，心衰左室功能不全患者中的猝死率占总死亡率的50%左右！！！ References: CHF-STAT: Singh SN. N Engl J Med .1995;333:77-82. GESICA: Doval, HC. Lancet. 1994;344:493-498. SOLVD: Cooper H. Circulation. 1999;100:1311-1315. V-HEFT I: Goldman S. Circulation. 1993;87(6 Suppl):VI24-31 MERIT-HF Investigators. Lancet 1999;353:2001-2007. CIBIS II Investigators. Lancet:353:9-13. USCHFT. Packer M. N Engl J Med 1996; 334:1349-1355. * * * On June 23rd of 2009, the principle investigators of the MADIT-CRT trial reported a 29% reduction with a p-value of 0.003 in mortality or heart failure interventions w