HPV检测在宫颈癌筛查和治疗中的的临床意义探析.doc

HPV检测在宫颈癌筛查和治疗中的临床意义探析 【摘要】目的 研究HPV检测在宫颈癌筛查和治疗中的的临床意义探析。方法 选取548名进入我院接受宫颈癌筛查的女性，先使用TCT进行检查的程序及结果表示为TCT检查，TCT检查后再使用HPV进行检查，过程及结果称之为HPV筛查，检查结果参照病理结果进行分析。结果 HPV和TCT阳性情况均与实际结果相同；HPV检查对良性炎症、CIN1、CIN2和CIN3的阳性率都远高于TCT检查的阳性检出率，具有明显差别。HPV阳性与实际阳性率相比没有太大区别，没有明显差别（P0.05）；HPV阳性与TCT阳性相比有很大区别，具有明显差别（P0.05）；TCT阳性与实际阳性率相比差别很大，具有明显差别（P0.05）。HPV阳性感染者中，有单一感染因素导致的疾病率要比多型感染导致的发病率多很多，具有明显差别（P0.05）。结论 HPV病毒与宫颈癌的严重程度有密切的相关性，对HPV进行筛查可以较准确的检侧出宫颈癌的发生情况，对宫颈癌的治疗及预防具有非常重要的临床意义。 【关键词】HPV病毒；宫颈癌；宫颈脱落细胞学检查；临床意义 Clinical Significance of HPV Detection in Cervical Cancer Screening and Treatment [Abstract]Objective To study the clinical significance of HPV detection in cervical cancer screening and treatment. Methods 548 women who entered our hospital for cervical cancer screening were selected to examine the procedure and the results of TCT examination, TCT examination, and then use HPV to check the process and the result is called HPV screening, and the results were analyzed according to the pathological findings. Results The positive detection rate of HPV and HPV was 100%, and the positive rate of TCT, CIN3, CIN2 and CIN1 was much higher than that of TCT, which had no significant difference compared with the positive rate (P0.05), and the positive rate of HPV was significantly different (P0.05). The positive rate of.HPV was significantly different (P0.05). The rate of incidence is much more than that of multiple infections, with a significant difference (P0.05). Conclusions HPV virus has a close correlation with the severity of cervical cancer, and it can be more accurate to screen HPV, which has a very important clinical significance for the treatment and prevention of cervical cancer. [Key words] Human papillomavirus screening; Cervical cancer; Cervical cytology; Clinical significance 宫颈癌(Cervical carcinoma)在世界范围内的发病率已经位居妇科肿瘤疾病的第二位[1]，每年全世界的病发人数超过了470000人次，因宫颈癌失去生命的有20多万人，其中有百分之八十的病人属于发展中国家[2]。宫颈癌是唯一找到致病原因的癌症，其是由于感染人类乳头瘤病毒(Human papillomavirus，HPV)引起的疾病[3]，在农村和偏远城镇的发病率远远高于大中型城市，这可能与人们的文化水平和卫生问题有关[4]