离子交换层析制备高纯度肝素和硫酸皮肤素-生物化学与分子生物学专业论文.docxVIP

华 华 中 科 技 大 学 硕 士 学 位 论 文 II II Abstract Heparin sodium and dermatan sulfate (DS) are both glycosaminoglycans, they are biological active and have a wide range of applications in medicine. Heparin sodium is mainly applied in clinical cardiovascular disease prevention and treatment, and as an anticoagulant and antithrombotic drug. Heparin is currently the most principal clinical applied anticoagulant, while DS can be used in treatment of osteparthropathy and hypertension disease. Since large quantities of DS was usually produced as byproducts during heparin industrial production from pig intes