对跨声门癌的再认识上海铁道大学医学院附属甘泉医院耳鼻喉科葛荣明.pptVIP

贯声门癌组织病理学研究和临床Histopathological Research of Transglottic Carcinoma 同济大学附属同济医院 耳鼻咽喉头颈外科 葛荣明 Rongming Ge Tongji Hospital of Tongji University,Shanghai Transglottic carcinoma Leroux-Robert(1936)最初描述 McGavran MH(1961)首次命名 Tucker GF(1962)提出声门旁间隙 Kirchner JA(1974)建议归入分型 吴学愚(1980)百科全书手术谈到 葛荣明(1981)国内首次组织病理证实 费声重、葛荣明(1986)作专题讨论 萧轼之(1989)专著引证采用 黄鹤年(1995)教科书采纳应用 除声门上型、声门型和声门下型外，在PGS直接跨越二区者如何归类？ Coronal topographic model about relationships of paraglottic space. Surgical specimen from a total laryngectomy which showed a characteristic transglottic growth. TGC is characterized by invasion of the paraglottic space. It invaded thyroid ala leterally and destroyed cricothyroid membrane inferiorly. Superficial mucosa of glottic area is relatively intact (serial section, HE dyeing, coronal site). The model showed the direction of extension of supraglottic carcinoma. The model showed the direction of extension of glottic carcinoma. Supraglottic carcinoma invaded into glottic and subglottic area from epiglottis, superficial mucosa of vocal cords were relatively intact.If it was managed by a horizontal supraglottic laryngectomy,the tumor would have been remained Supraglottical tumor had not invaded glottic area although it was large enough to invade preepiglottic space An another section of laryngeal specimen was similar to thereinbefore in the same region of tumor The tumor of laryngeal surface of epiglottis had already invaded preepiglottic space by small holes of epiglottis,but had not reached to the anterior commissure anteroinferiorly. Supraglottic carcinoma could not invade glottic area in the ventricle laterally because of the effects of the barriers. TGC destroyed the thyroid cartilage laterally in PGS and invaded both the supraglottic and infraglottic divisions of the larynx. Tran