MHC主要组织相容性复合体ppt课件.pptVIP

(1) Antigen presentation (2) MHC restriction (3) T cell development in thymus (4)Induce homograft rejection (5)Genetic control the immune response Functions of MHC Molecules （1）Antigen presentation Peptide-MHC complex peptides of 8-10 amino acids endogeneous antigens peptides of 13 amino acids exogenous antigens b2-M a-chain Peptide a-chain b-chain Peptide Differences in Ag presentation MHC class I MHC class II Cell surface peptides of Ag Antigen recognition by T cells requires peptide antigens and presenting cells that express MHC molecules Y T T cell response No T cell response No T cell