碳糊电极上有机药物的吸附催化伏安法分析与抗癌药物与DNA相互作用电化学分析.pdfVIP

丁永兰: 碳糊电极上有机药物的吸附催化伏安法研究及抗癌药物与DNA 相互作用电化学研究 for the determination of vitamin K . The effective factors on the system 3 were investigated, and a new method for the determination of vitamin K3 was established. And the oxidant is dissolved oxygen in the system. In 0.30 M NH .H O-NH Cl buffer (pH 8.2), 0.0 V accumulation potential 3 2 4 was applied to a carbon paste electrode for 60 s, and the 2nd–order derivate voltammogrames were recorded by applying a negative–going potential scan from 0.0 to –1.0 V at 400 mV/s. The peak current is linearly proportional to the vitamin K3 concentration in the range of -10 -8 -8 5×10 mol/L ～1.0×10 mol/L (accumulation 90s) and 1.0×10 mol/L ～2.5×10-7 mol/L (accumulation 60s) with the correlation -10 coefficient of 0.9941 and 0.9972. The limit of detection is 1.5 ×10 mol/L for 90 s accumulation. The voltammetric behavior of vitamin K3 at a CPE was studied by cyclic voltammetry. The method was applied to the direct determination of vitamin K3 in clinical injection samples with satisfactory results. In chapter three, a novel electroanalytical method has been described for the first time to the determination of adriamycin. Experiment found that adriamycin yields an adsorption catalytic voltammetric peak in 0.10 mol/L H BO -Na BO buffer solution (pH 8.5) 3 3 2 7 at a carbon paste electrode (CPE). The second-order derivative p