中文题目右美托咪定减少剖宫产后不良反应的作用英文题目Effectsof.PDFVIP

中文题目 右美托咪定减少剖宫产后不良反应的作用 英文题目 Effects of dexmedetomidine in reducing post-cesarean adverse reactions. 译 者：易菁 背景和目的：本研究的目的是评估右美托咪定（Dex）对剖宫产后疼痛的控制和 不良反应的影响。 方法：共纳入 80 名采用腰硬联合麻醉的产妇，随机分为试验组（D 组）和对照 组（C 组）（n=40）。其中，D 组采用的麻醉药物为盐酸罗哌卡因联合右美托咪 定；C 组采用的麻醉药物为盐酸罗哌卡因联合吗啡。随后分别于 2,6,12 以及 24h 时采用 Ramsay 镇静评分和视觉模拟评分（VAS）评估了镇静情况，静息和 咳嗽状态的镇痛情况和药物使用相关的不良反应。 结果：除剖宫产后 2h 外，其余时点静息和咳嗽状态 D 组的 VAS 评分均低于 C 组 （P＜0.05）；剖宫产后 12h 时 D 组的 Ramsay 镇静评分低于 C 组（P＜0.05）， 其余时点两组的 Ramsay 镇静评分无差异；D 组恶心，呕吐以及瘙痒的发生率均 显著低于 C 组（P＜0.05）。 结论与讨论：剖宫产中右美托咪定（Dex）的使用可提高局部麻醉方式的镇痛效 果，增强腰硬联合麻醉产后的镇静作用和减少剖宫产后药物使用的不良反应发 生率。 原始文献摘要 引用格式 Mo Y, Qiu S. Effects of dexmedetomidine in reducing post-cesarean adverse reactions.[J]. Experimental and therapeutic medicine, 2017,14(3):2036-2039. DOI:10.3892/etm.2017.4759 Abstract ： This study evaluated the analgesia effect and the effect on adverse reaction of using dexmedetomidine (Dex) in post-cesarean section. Eighty women who had been performed caesarean delivery with combined spinal and epidural anesthesia were selected. The experimental group (group D) included 40 random patients and the control group (group C) included the other 40 women. Patients in group D were given ropivacaine hydrochloride and Dex while patients in group C were given ropivacaine hydrochloride and morphine. We assessed and recorded the patient status at 2, 6, 12, 24 and 48 h using Ramsay sedation scale and visual analogue scale (VAS) in resting state and coughing state and we also recorded their adverse reactions. Except for the first 2 h after surgery, group D gets a lower VAS score than group C all the time in either resting state or coughing state (p0.05); at 12 h, group D had a lower Ramsay score than group C (p0.05) and no significant difference during the rest of the time was found; group D had a significantly lower rate of nausea, emesis and pruritus than group C (p0.05). In conclusion, the usage of Dex in analgesia for post-cesarean can