高清白光模式与高木清白光i-scan模式对结直肠息肉检出的前瞻性随机对照研究.docxVIP

西南医科大学硕士学位论文床意义尚待进一步研究。 西南医科大学硕士学位论文 床意义尚待进一步研究。 关键词：高清白光(Ⅷ)+)肠镜；i-Scan；结直肠息肉；息肉检出率 万方数据 西南医科大学硕士学位论文Comparative 西南医科大学硕士学位论文 Comparative study of high definition colonoscopy and high definition colonoscopy plus i-Scan imaging system in the detection of colorectal polyps：a prospective，randomized，controlled trial Abstract：Background：Colorectal cancer(CRC)is one of the most common malignant tumors in the gastrointestinal tract，with its morbidity and mortality rates rank the 3rd and 4th respectively among all malignancies．More than 80％of CRC develop from colorectal adenoma，and colonoscopic removal of adenoma reduces up to 76％to 90％of CRC incidence．So a high adenoma detection rate is vital to prevent CRC．But according to a recent study of colonoscopy,adenoma miss rate could be 22％．Hence improvement of adenoma detection rate，which cannot be achieved without increasing polyp detection rate at the first place，is significant for CRC prevention．bjective：To investigate the usefulness of i-Scan in the detection of colorectal polyps as a routine diagnostic procedure via a prospective randomized controlled trial comparing colorectal polyps detection rates of high definition colonoscopy and high definition colonoscopy plus I-scan imaging system．Methods：Sample size is determined according to calculation formula of quantitative data sampling． Consecutive individuals who had never underwent colonoscopy before and don’t fulfill any exclusion criterion were assigned to i-Scan group or control group with strict randomization concealment．Random numbers were generated by SPSS software version 22．0．Intubation of the cecum was completed with ．4． 万方数据 西南医科大学硕士学位论文high 西南医科大学硕士学位论文 high definition white light for both groups，while withdrawal was performed with additional i-scan SE+4／CE+2 mode for i-Scan group，and merely with high definition white light for control group．Withdrawal procedure were video recorded and withdrawal time was required to be at least 7 min．The location， character and