TBX2、PAX9在卵巢上皮性癌中的表达及临床意义.pdfVIP

英文摘要 The ofTBX2，PAX9in ovariancancerand expression epithelial itsclinical significance ABSTRACT ovariancancerthe has inthe Objective：Epithelial highestmortality female tract ofovarian reproductivemalignanttumor，The earlysymptoms cancer vast of at patientslack，themajorityrapidprogress，arediagnosed advanced inthe isstill stages，Manypatients operationplus chemotherapy todisease orrecurrenceinashort likely progression appeared time，Therefore， tofurther themechanismof ovariancanceroccurrenceand clarify epithelial the and development，forearlyeffectivetumormarkersand of screeninggreat tothe of significance．TBX2 belongsdevelopmentalregulationtranscription factor one ofthemembersofT—BOX a gene，is is new genefamily；PAX9 memberofthePAX essentialfor of family，is regulationgene expression recent foundthe ofthe duringembryogenesis．In years，thestudy upregulation of