论文--鼠神经生长因子穴位注射治疗儿童脑瘫伴言语障碍疗效观察.docVIP

PAGE PAGE 4 鼠神经生长因子穴位注射治疗儿童脑瘫伴言语障碍疗效观察 [摘要]目的：探讨鼠神经生长因子（NGF）穴位注射结合言语训练治疗儿童脑瘫伴言语障碍的临床疗效。方法：将123例言语障碍的患儿，随机分为治疗组62例，对照组61例，2组均采用相同言语训练治疗及穴位注射，但对照组使用维生素B6注射液，而治疗组使用NGF18μg（≥9000AU）/支，隔日1次，每次4-6个穴位，14次为一个疗程，停药7天后进入下一个疗程，连续治疗6个疗程。结果：治疗后2组患儿言语功能均改善，治疗组优于对照组（P0.05），差异有统计学意义；结论：NGF穴位注射结合言语训练能更好的提高儿童脑瘫伴言语障碍的疗效。 [关键词]儿童脑性瘫痪 言语障碍 鼠神经生长因子 Mouse nerve growth factor acupoint injection in the treatment of Cerebral Palsy with children and Speech disorder effect [Abstract] Objective: To explore the clinical curative effect of NGF acupoint injection combined with speech training in treatment of children with Speech disorder. Methods: 123 cases of children with Speech disorder were randomly divided into the treatment group of 62 cases, 61 cases of the control group and 2 groups had the same speech training therapy and point injection, but the control group used vitamin B6 injection, and the treatment group,NGF18μg(≧9000AU)/ support, tertian 1, every time 4-6 points, 14 times as a course of treatment, drug withdrawal 7 days into the next course, 6 course of treatment. Results: After treatment in 2 groups with speech function were improved, in treatment group than in control group ( P0.05 ), the difference was statistically significant; Conclusion: NGF acupoint injection combined with speech training can improve the effect of language development delay in children. [Key words] Cerebral Palsy with children Speech disorder mouse nerve growth factor 小儿脑瘫为自受孕开始至婴儿期非进行性脑损伤和发育缺陷所导致的综合征，主要表现为运动障碍及姿势异常[1]。脑瘫儿童大多存在着不同程度的语言障碍。表现为发音不清，或严重失语。造成的原因主要有：构音器官的运动障碍、语言中枢的障碍、构音器官和语言中枢同时存在障碍，言语障碍最开始表现为吸吮困难及吞咽咀嚼困难[2]。随着年龄的增长，有的几乎不能发出任何声音，有的在交流与理解方面存在不同程度的障碍，严重影响患儿的身心发育。儿童脑瘫伴言语障碍主要表现为：运动性构音障碍和语言发育迟缓。 运动性构音障碍是由于神经肌肉病变引起构音器官的运动障碍，出现发声和构音不清等症状[3]。 语言发育迟缓是指在发育过程中的儿童语言发育没有达到与其年龄相应的水平，呈现语言发育迟缓的儿童多数具有精神及对周围人反应的发育延迟或异常[4]。湘雅博爱康复医院儿童康复中心和广州中医药大学附属南海妇产儿童医院，自2012年6月以来采用NGF穴位注射，治疗儿童脑瘫伴言语障碍62例，取得了较好的疗效，现报道如下： 1.临床资料 1.1一般资料 123例脑瘫伴言语障碍的患儿，随机分为治疗组62例和对照组61例。治疗组中男37例，女25例，年龄1岁至6岁，平均（3.3±1.1）；对照组中男35例，女26例，年