磁场的细胞生物学效应不统一之现状分析.pdfVIP

网络出版时间：2014-08-25 14:34 网络出版地址：/kcms/doi/10.11844/cjcb.2014.09.0133.html 中国细胞生物学学报 Chinese Journal of Cell Biology 2014, 36(9): DOI: 10.11844/cjcb.2014.09.0133 磁场的细胞生物学效应不统一之现状分析 陈 薇 刘娟娟 罗 艳* ( 中国科学院合肥物质科学研究院, 强磁场科学中心, 合肥 230031) 摘要 随着无线电通讯设备和家用电器的日益普及, 磁场对生物体健康的影响越来越受到 人们的关注。目前, 已有一些磁场对细胞影响的初步探索, 但是由于现有研究中各种细胞的差异、 磁场参数的不同, 影响了人们对磁场的细胞生物学效应的正确认识。该文将系统比较目前此领域 研究成果, 分别从磁场类型和强度、细胞种类及密度等方面来阐明磁场对细胞增殖的影响, 并且通 过分析磁场对细胞信号通路的影响来探究磁场生物学效应的潜在机制。该文旨在对现有的结论进 行总结分析并且找到存在差异和矛盾的原因, 从而为该领域的深层次探讨提供线索, 为进一步在基 础和临床研究中探究磁场生物学效应提供可借鉴的依据。 关键词 磁场; 细胞增殖; 信号通路; 生物学效应 Analysis of the Inconsistency Among Current Studies Reporting Biological Effects of Magnetic Fields On Cells Chen Wei, Liu Juanjuan, Luo Yan* (High Magnetic Field Laboratory, Chinese Academy of Sciences, Hefei 230031, China) Abstract With the development and increasing popularity of the wireless communication equipments, the potential impact of magnetic fields on human health is invoking increasing concerns. Due to the differences between cell types as well as magnetic field parameters, people have not correctly understood the mechanism of the biological effects caused by the magnetic field. This review gives an overview of the current results of scientific research regarding in the effects of magnetic field on cell proliferation, taking magnetic field type and intensity, cell type and density into account. Futhermore, some potential biological mechanisms by analyzing the magnetic effects on signal transduction pathways are also discussed in this review. To provide some starting po