磁共振成像对宫颈癌小淋巴结转移的诊断价值和对放射-肿瘤防治研究.PDF

920 2014 41 8 Cancer Res Prev Treat,2014,Vol.41,No.8 · · 肿瘤防治研究 年第 卷第 期 doi:10.3971/j.issn.1000-8578.2014.08.014 · · 临床诊断 磁共振成像对宫颈癌小淋巴结转移的诊断 价值和对放射治疗靶区设计的影响 1 1* 2 3 2 1 1 黄叶才 ，漆云翔 ，任静，范习刚，杨学刚，李芷茹，郎锦义 Diagnostic Value of MRI in Detection of Small Lymph Node Metastasis and Its Effects on Radiotherapy Target Volume Design in Cervical Cancer Patients 1 1* 2 3 2 1 HUANG Yecai , QI Yunxiang , REN Jing , FAN Xigang , YANG Xuegang , LI Zhiru , LANG Jinyi1 1. Department of Radiation Oncology,Sichuan Cancer Hospital,Chengdu 610041,China,2. Department of Imaging;3.Department of Oncology, Deyang People’s Hospital(*: Contributed Equally as First Author) Corresponding Author:LANG Jinyi,E-mail:langjy610@163.com Abstract: Objective To explore the diagnostic value of magnetic resonance imaging(MRI) in the detection of small lymph node(LN) metastasis and its effect on radiotherapy target volume design in cervical cancer patients. Methods We collected 37 patients with cervical cancer diagnosed pathologically in Sichuan cancer hospital.They were all received preoperative MRI scan and enhanced scan. Combined with T1WI enhanced sequence, the longest diameter and shortest diameter of visible lymph nodes on T2WI were measured respectively ，and the morphological features such as enhancement patterns ，extra capsular spread(ECS), edge of the lymph nodes andcapsular invasion were recorded. Results Short diameter of metastatic LN was longer than that of non-metastatic LN statistically(P=0.01).Area under curve(AUC) of short diameter in receiver operator characteristic curve ROC) was larger th