血清胆红素与颅内外动脉粥样硬化地相关性分析.docxVIP

英文论著摘要 The Correlation Analysis of Serum Bilirubin Concentrations and Cerebral Atherosclerosis objective To investigate the relationship between the serum bilirubin and incidence of cerebral atherosclerosis as well as new cerebral infarction，and thereby provide reference to cerebral atherosclerosis risk and the possibility of new—onset stroke． Methods Analyze retrospectively patients of Neurology in Shen舀ing hospital affiliated to China Medical University from October 201 1 to March 2014．1 16 patients with intracranial and extracranial atherosclerosis are divided into three groups：1)Carotid atherosclerosis group(CAS，40 cases)；2)Intracranial atherosclerosis group(ICAS，36 cases)；3)Carotid and intracranial atherosclerosis group(CAS+ICAS，40 cases) according to IMTI．3mm and intracranial lumen lost50％．Take 39 cases without cerebral vascular stenosis and cerebral infarction as the control group for the same period．Measure serum bilirubin and analyze the difference between them．Then 1 1 6 patients with atherosclerosis are divided into new cerebral infarction group(49 cases) and obsolete cerebral infarction group(76 cases)and measure the serum bilirubin respectively to know the impact on serum bilirubin because of new infarction．All data are presented as the mean 4-the standard error．Take SNK·q test between groups and use t-test to compare means．Enumeration data take single factor analysis and measurement data take significance test．Multivariate analysis uses the unconditioned Logistic regression，with a significance limit of P0．05．Data are analyzed by SPSS 1 7．0 software packet． Result 1．The group of CAS，ICAS and CAS+ICAS have a lower level in serum direct bilirubin，indirect bilirubin and total bilirubin，and the difference iS statistically significant(P0．05)； 3 2．Carotid atherosclerosis group，intracranial atherosclerosis group and group of carotid and intracranial atherosclerosis show no significant difference between them (尸0．05)，bu