Laryngeal tumours and radiotherapy dose to the cricopharyngeus are predictive of death from iration pneumonia.喉肿瘤和放疗剂量cricopharyngeus是吸入性肺炎死.pdfVIP

Oral Oncology 64 (2017) 9–14 Contents lists available at ScienceDirect Oral Oncology journal homepage: www. /locate/oraloncology Laryngeal tumours and radiotherapy dose to the cricopharyngeus are predictive of death from aspiration pneumonia Jolyne O’Hare a,⇑, Julia Maclean b,d, Michal Szczesniak c,d, Rashmi Gupta a, Peter Wu c, Harry Quon e, Ian Cook c,d, Peter Graham a,d a Department of Radiation Oncology, St George Hospital, Sydney, NSW, Australia b Speech Pathology Department, St George Hospital, Sydney, NSW, Australia c Department of Gastroenterology and Hepatology, St George Hospital, Sydney, NSW, Australia d St George Clinical School, University of New South Wales, Sydney, NSW, Australia e Department of Radiation Oncology Molecular Radiation Sciences, Johns Hopkins University, School of Medicine, Baltimore, MD, USA a r t i c l e i n f o a b s t r a c t Article history: Objectives: Aspiration pneumonia is an under-reported treatment sequelae following radiotherapy for Received 27 September 2016 head and neck cancer (HNC) patients. This study aims to investigate its incidence and risk factors in this Received in revised form 19 November 2016 population. Accepted 22 November 2016 Materials and methods: A retrospective review of all HNC patients that had received radiotherapy or Available online 29 November 2016 chemo radiotherapy with radical intent at a single institution was undertaken (n = 206). Dose delivered