09级5年制本科肾衰.pptVIP

* 第十六章 肾功能不全 Renal Insufficiency 【Pathogenesis of renal disease】 Renal Insufficiency Renal Failure Uremia 一、肾功能不全（Renal Insufficiency ） （一）概念（Concept） 当各种病因引起肾功能严重障碍时，会出现多种代谢产、 药物和毒物在体内蓄积，水、电解质和酸碱平衡紊乱，以 及肾脏内分泌功能障碍的临床表现。 The majority of diffuse renal disease result in progressive loss of these nephrons, whereas undamaged nephrons function normally to regulate body fluid and maintain a balance between intake and output of various dietary constituents. In renal insufficiency, the kidneys are unable to clear the blood of urea and creatinine which are waste products of metab