五碳糖发酵生产乙醇的菌种研究进展.docxVIP

贺应龙 ，熊兴耀 *，苏小军（1.湖南农业大学 园艺园林学院 贺应龙 ，熊兴耀 *，苏小军 （1.湖南农业大学 园艺园林学院，湖南 长沙 410128；2.作物种质创新与资源利用国家重点实验室培养基地，湖南 长沙 410128) 摘 要：当前以木质纤维素为原料制备燃料乙醇已成为全球研究热点，发酵五碳糖产乙醇的菌种选育是其关键技术之一。文中综述 了微生物发酵五碳糖产乙醇的机理，五碳糖发酵自然微生物的种类及菌种遗传改良的研究进展，并对今后菌种的研究方向进行了简 要论述。 关 键 词：五碳糖；乙醇；发酵；改良 中图分类号：TQ223.1 文献标识码：A 文章编号：0254-5071（2010）04-0008-04 Research progress in microorganism for ethanol fermentation by pentose HE Yinglong1, 2, XIONG Xingyao1, 2*, SU Xiaojun2 (1.College of Horticulture and Landscape, Hunan Agricultural University, Changsha 410128, China; 2.Pre-State Key Laboratory for Germplasm Innovation and Utilization of Crop, Changsha 410128, China) Abstract: Bioconversion of lignocelluloses to ethanol has become a global research focus in recent years. The breed of microbes for fermenting pen- tose to ethanol is one of the key technologies. The mechanism of bioconversion of pentose to ethanol is introduced in this paper. The advances on the natural strains of pentose fermentation and genetic improvement were reviewed. In addition, the research prospect was discussed. Key words: pentose; ethanol; fermentation; improvement 由于石油等化石能源的大量开采，消耗过快，石油资 源储备已经到了濒临枯竭的地步。因此，寻找一种化石能 收稿日期：2009-12-23 基金项目：国家重点基础研究发展计划（973计划）（2009CB226108） 作者简介：贺应龙（1985-），男，湖南宁乡人，在读硕士研究生，主要从事生物质能源研究工作；熊兴耀*，教授，通讯作者。 !!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!! biosynthesis[J]. Sci, 1999, 284(5418):1368-1372. [14] HENDRICKSON L, DAVIS C R, ROACH C, et a1. Lovastatin biosynthesis in Aspergillus terreus: Characterization of blocked mutants enzyme activities and a multifunctional polyketide synthase gene[J]. Chem Biol, 1999, 6(7): 429-4391. [15] AUCLAIR K, KENNEDY J, HUTCHINSON C R, et a1. Conversion of cyclic Nonaketides to lovastatin and compactin by a lovv deficient mutant of Aspergillus terreus [J]. Bioorg Med Chem Lett, 2001, 11 (12):1527-1531. [16] MANZONI M, ROLLINI M. Biosythesis and biotechnological production of statins by filamentous fungi and application of these cholesterol-lowing drugs [J]. Appl