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* A bit of comic relief: This slide emphasizes the need for proper decontamination suits. * APPLIES TO ALL CHEMICAL AGENTS DISCUSSED PPE – proper protective equipment * * Up to 100 mg of atropine has been required in severely intoxicated patients following organophosphate poisoning. Picture – Atropine compound * Atropine will treat SLUGBAM symptoms (smooth muscles) – doesn’t hurt to inject 2-PAMCl will treat muscular and neurologic symptoms – does hurt to inject AGING: after a certain amount of time, can’t stop; for example, epoxy glue (for a period of time you can separate, but it will eventually bond) Sarin (5 hours) and Soman (2 minutes)“ages” quickly, the bond is irreversible – on site treatment gets maximal benefit. MarkI:2 mg of atropine in 0.7 ml diluent 600 mg of 2-PAMCl in 2 ml diluent * AGING: after a certain amount of time the effects become irreversible; for example, epoxy glue (for a period of time you can separate, but it will eventually bond) Sarin (5 hours) and Soman (2 minutes)“ages” quickly, the bond is irreversible – on site treatment gets maximal benefit. * 3 multiple choice questions to be answered following the case presentation and discussion. * The correct answer is: b. The walking wounded and hysterical patients often overload the medical system * The correct answer is: c. Pinpoint pupils * The correct answer is: d. Atropine * End presentation and distribute activity survey. Name Synonym Aging T1/2 Sarin GB ~5 hours Soman GD ~2 min Tabun GA 40 hours VX None 40 hours “Aging” Nerve Agent Questions What was the public health lesson learned from the 1995 Sarin terrorists attack in the subway system of Tokyo, Japan? This bioterrorist attack could only occur in a large city with an enclosed underground subway system. The walking wounded and hysterical patients often overload the medical system Religious cults should be placed under strict federal surveillance Ample supplies of the antidotes are readily available Question #1 In
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