自身免疫性干眼调节T细胞及细胞因子的表达.pdf

Int Eye Sci,Vol.17,No.3,Mar. 2017摇 摇 http:/ / Tel:029 摇 Email:IJO.2000@163.com ·实验论著 · 自身免疫性干眼调节T 细胞及细胞因子的表达 1 2 朱摇 峰 ,柯摇 峰 作者单位:(442000)中国湖北省十堰市中医医院眼耳鼻喉1 0.05),andthetearof the model groupwas significantly 2 科;(442000)中国湖北省十堰市人民医院眼科 lower than that of the control group (P0. 05). The 作者简介:朱峰,男,主治医师,研究方向:白内障、青光眼。 expressionof IL-17, TNF-琢, TGF-酌 and IL-6 in the 通讯作者:柯峰,男,硕士,主治医师,研究方向:白内障、青光 modelgroup were significantly higher than those in the 眼.2173581197@ controlgroup (P0.05). The expression of IL-10 and 收稿日期:2016-10-13摇 摇 修回日期:2017-02-16 TGF-茁 was significantly lower than those of the control + + group (P0郾05). The ratio of CD4 CD2 Treg cells in Experimentalstudy ontheexpressionof T lacrimal gland tissue and spleen was higher in control + + cells and cytokines in the regulation of group. The proportionof CD4 CD25 Treg cells in model groupdecreased (P0.05). autoimmune dry eye 誗CONCLUSION:IL-17,TNF-琢, IL-6 and TGF-酌 play important roles in inflammatory reaction of lacrimal 1 2 F