生物可降解材料聚乙二醇_聚乳酸_聚谷氨酸三_省略_段共聚物与人脐静脉内皮细胞的相.docVIP

Basic Medicine 中国组织工程研究与临床康复 第 12 卷 第 10 期 2008–03–04 出版 Journal of Clinical Rehabilitative Tissue Engineering Research March 4, 2008 Vol.12, No.10 Cytocompatibility of biodegradable poly(ethylene glycol-b-poly(L-lactide-b-poly(L-glutamic acid tri-block copolymer with human umbilical vein endothelial cells☆ Liu Bin1, Song Xian-jing2,3, Liu Jie-yu3, Jiang Feng4, Shi Yong-feng1, Shuang Dong-si1, Li Zhi-bo1 Second Hospital, Jilin University, Changchun 130041, Jilin Province, China; 2 China-Japan Union Hospital, Jilin University, Changchun 130041, Jilin Province, 3 China; Changchun Centre Hospital, Changchun 130041, Jilin Province, China; 4 Chengde Medical College Affiliated Hospital, Chengde 067000, Hebei Province, China Liu Bin☆, Doctor, Professor, Second Hospital, Jilin University, Changchun 130041, Jilin Province, China Songxianjing2007@2008.sin Received: 2007-11-03 Accepted: 2008-01-14 (07-50-11-6029/YWY Liu B, Song XJ, Liu JY, Jiang F, Shi YF, Shuang DS, Li ZB. Cytocompatibility of biodegradable poly(ethylene glycol-b-poly (L-lactide-b-poly (L-glutamic acid tri-block copolymer with human umbilical vein endothelial cells.Zhongguo Zuzhi Gongcheng Yanjiu yu Linchuang Kangfu 2008;12(10: 1950-1953(China [/ zglckf/ejournal/ upfiles/12-10/ 10k-1950(ps.pdf] 1 Abstract BACKGROUND: Poly(ethylene glycol-b-poly(L-lactide-b-poly(L-glutamic acid (PEG-PLA-PGL tri-block copolymers have good applied foreground in constructing tissue engineering scaffold materials. Whether endothelial cells survive and grow on the materials has a direct influence on the application as a biodegradable material for the scaffold of endothelial cell vector. OBJECTIVE: To explore the cytocompatibility of PEG-PLA-PGL tri-block copolymers with human umbilical vein endothelial cells (HUVECs. DESIGN: Randomized control observation. SETTING: the Second Hospital of Jilin University. MATERIALS: The experiment was carried out in the Department of Pathobiology, School of Basic Medical Sciences, Jilin University