2015留学生心绞痛.pptxVIP

28Antiangina Pectoris Agents §1 Brief IntroductionCoronary heart disease Teatment of Angina Pectoris:1. Dilation of blood vessels2. Reducing blood lipid level3. Reducing blood glucose level4. Antithrombosis5. Anti-painAnti-angina pectoris AgentsContractilityHeart RateCardiac Wall TensionPreload and Afterload1. Beta-Blockers2. Glyceryl trinitrate 3. L-CB Coronary heart disease prescription:Nitrate estersAntihypertensive agentsAntilipemic agents §2 Nitrate Vasodilator Blood vessel dilation mechanismIn blood vessel wall, GTN produce NO with the help of mitochondrial aldehyde dehydrogenase (mtA