房颤合并肾功能不全的 抗凝治疗.ppt

* Modification of diet in renal disease study (MDRD)?肾脏病膳食改良试验 * 研究介绍 * Non-end stage chronic kidney disease Patients with chronic kidney disease who did not require renal-replacement therapy were defined as patients with non–end-stage chronic kidney disease * 美国指南 2014 2014 房颤 中国 * * CrCl ranges: *Mild: apixaban 51–80 ml/min; dabigatran N/A (50–80 ml/min); rivaroxaban 50–80 ml/min #Moderate: apixaban: 30–50 ml/min; dabigatran 30–50 ml/min; rivaroxaban 30–50 ml/min ?Severe: apixaban 15–29 ml/min; dabigatran 10–30 ml/min; rivaroxaban 15–20 ml/min §Range and ratio based on Stangier et al.