纳洛酮联合依达拉奉治疗急性脑血管病意识障碍疗效观察.pdfVIP

DOC格式论文，方便您的复制修改删减 纳洛酮联合依达拉奉治疗急性脑血管病 意识障碍疗效观察 （作者:___________单位: ___________邮编: ___________） 【摘要】目的观察纳洛酮联合依达拉奉治疗急性脑血管 病意识障碍的疗效。方法 将入选的急性脑血管病意识障碍患者118 例随机分为治疗组60 例和对照组58 例，对照组给予西医常规治疗; 治疗组在对照组常规治疗的基础上加用纳洛酮和依达拉奉静滴。2 组 均连续用药14 d。观察2 组总有效率和意识障碍恢复时间。结果 治 疗后治疗组总有效率显著高于对照组(P0.05);治疗组3 个时间段意识 障碍恢复时间显著短于对照组(P0.05)。结论 纳洛酮联合依达拉奉能 显著缩短急性脑血管病意识障碍恢复时间，促进神经功能的恢复。 【关键词】急性脑血管病;意识障碍;纳洛酮; 依达拉 【Abstract 】 Objective To observe the clinical effect of naloxone joint edaravone on acute cerebrovascular disease with disturbance of consciousness. Methods One hundred and eighteen patients with acute cerebrovascular disturbance of consciousness were randomly divided into treatment group(60 cases) and control DOC格式论文，方便您的复制修改删减 group (58 cases).Control group was given conventional western medical treatment, Treatment group received intravenous infusion o naloxone and edaravone on the basis o conventional therapy.Two groups were continuous medication 14 days.The two groups overall e iciency and awareness o barriers to recovery time were observed. Results After treatment, the total e ective rate o treatment group was significantly higher than control group(P0.05); Three time periods of disturbance of consciousness recovery time o treatment group was significantly shorter than control group(P0.05). Conclusion Naloxone combined edaravone can significantly reduce the disturbance of consciousness recovery time with acute cerebral vascular disease, promote the recovery o neurological function. 【Key words】Acute cerebrovascular disease; Disturbance o consciousness; Naloxone; Edaravone 急性脑血管病是临床常见病，其发病率和致残率均较高，其中 意识障碍患者占较高比例，急性期意识障碍恢复的迟早及程度直接影 响预后。纳洛酮具有减轻脑缺血再灌注损伤从而改善神经功能缺损等 作用[1]。而依达拉奉是一种自由基清除剂，其良好的脑保护作用得到 国内外临床研究的证实。我院于2008 年应用纳洛酮联合依达拉奉治 疗急性急性脑血管病意识障碍