《进化生态学》生态基因组学.pptx

Nothing in Biology Makes Sense Except in the Light of EvolutionTheodosius Dobzhansky (1900-1975)，院 11 II 帽l‘”·· 、··· ·”’ · ‘ ·”Ecological Genomicsin the light of evolution陈兵，康乐中国科学院动物研究所ContentsWhat is Ecological Genomics (EG)：definition,aims, category researchersCurrent research directions / focus in EGModern methodologies adopted by EGMajor research progress - case studiesThe future of EGQuestions involved in ecological genomicsWhat are the genome-wide patterns of gene expression in organisms under physiological or metabolic stress?How are microbial communities structured, and how do they vary over ecological gradients?How are life history patterns and mating systems influenced by genomicvariation?What is the genomic basis of phenotypic plasticity?What genes or genetic markers underlie adaptive traits?How do epigenetic modifications of genomes affect ecologically important traits?(Patrick Abbot 2015)? …What is ecological genomics?(Ungerer et al. 2008)These responses include modifications of biochemical, physiological,morphological, or behavioral traits of adaptive significance.Definition: what is ecological genomics?An integrative field of study that seeks “to understand genomic responses to environmental variation and in turn how genomic variation shapes the responses of organisms to their environment.”(Patrick Abbot 2015)…to understand the genetic mechanisms underlying adaptive responses of organisms to their environment.- from genetic perspective/)(h/)t/)t/)p/):/)///)e/)c/)o/)g/)e/)n/)./)k-/)s/)t/)at/)e/)./)e/)d/)u/)/)Distinct nature of Ecological Genomics“embodies Darwin’s four main questions but restates them in a modern context that spans multiple research levels.”GIt is an interdisciplinary field.The incorporation of genomic tools now allows us to open the black box between environment and phenotype, and to try to understand the mechanisms behind adaptation.Distinct nature of Ecological Genomicsexpanding from model species to non-model species, with deve