病理学教学课件：泌尿系统疾病.pptVIP

The microscopic appearance of the end stage kidney is similar regardless of cause, which is why a biopsy in a patient with chronic renal failure yields little useful information. The cortex is fibrotic, the glomeruli are sclerotic, there are scattered chronic inflammatory cell infiltrates, and the arteries are thickened. Tubules are often dilated and filled with pink casts and give an appearance of thyroidization.“ Light microscopy shows hyaline obliteration of glomeruli, transforming them into acellular hyaline masses made of mesangial matrix, basement-membrane material, dense collagen, and