糖尿病视网膜病全英.pptVIP

DIABETIC RETINOPATHY Prof. Raj Vardhan Azad Diabetes: Global Perspective Diabetes – Challenges ? Total no of people with diabetes is projected to rise 171 million 2000 to 366 million in 2030 ? DR is the 3 rd leading cause of visual impairment among inner city Adults ≥ 40 yrs of age. ? Biochemical mechanisms ? Capillaropathy ? Haematological changes ? Microvascular occlusion PATHOGENESIS DR 糖尿病视网膜病的发病机理 ANGIOGENIC FACTORS Hypoxia ↑ VEGF BRB breakdown And new vessel formation 组织缺氧 血管内皮细胞生长因子数量上升 视网膜屏障与新生血管形成 CLINICAL FEATURES 临床特征 ? Microaneurysms 微动脉瘤 ? Hemorrhages 眼底出血 ? Soft Exudates 血管