大叶桉煎剂浸浴联合短波紫外线照射对深度烧伤残余创面愈合及血清IL-1β、TNF-α、IL-6表达的影响.docxVIP

大叶桉煎剂浸浴联合短波紫外线照射对深度烧伤残余创面愈合及血清IL-1β、TNF-α、IL-6表达的影响 Effects of Bathing with Eucalyptus Grandis Decoction Combined with Short-wave Ultraviolet Irradiation on Wound Healing and Expression of Serum IL-1β， TNF-α， IL-6 in Residual Wounds of Deep Burns LAN Hong-wei1，ZHOU Zhong-zhi1，ZOU Mei-lin1，FENG Shui-hua2 （1.Department of Burn， Sores and Plastic Surgery;2.Department of Anesthesiology， the First Affiliated Hospital of Hunan University of Traditional Chinese Medicine，Changsha *****，Hunan，China） Abstract： Objective To investigate the effect of bathing with Eucalyptus grandis decoction combined with short-wave ultraviolet irradiation on wound healing and expression of serum interleukin-1β （IL-1β）， tumor necrosis factor-α （TNF-α） and interleukin-6 （IL-6） in deep burn residual wounds. Methods A total of 147 patients with residual burn wounds in our hospital from August 2017 to December 2019 were selected for a prospective randomized controlled study， and they were divided into the combined group （n=49）， the control group A （n=49）， and the control group B （n=49） using a computer-generated random number table. On the basis of conventional treatment， the control group A was given short-wave ultraviolet irradiation， the control group B was given a bath with Eucalyptus grandis decoction， and the combined group was given a bath with Eucalyptus grandis decoction combined with short-wave ultraviolet irradiation， all of which continued treatment for 2 weeks. Compared the efficacy， residual wound repair status， the positive detection rate of bacteria in the wound and the Visual analogue scale （VAS）， Self-rating anxiety scale （SAS）， and serum growth factor indicators [Epidermal growth factor （EGF）， Transforming growth factor-α （Transforming growth factor-α， TGF-α）]， IL-1β， TNF-α， IL-6 expression before and after treatment for 2 weeks of the three groups. Results The total effective rate of the combined group after 2 weeks of treatment was higher than that of the co