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- 2021-02-27 发布于天津
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壳核出血患者记忆障碍的主因:丘脑皮质束损伤?
来自韩国Yeungnam大学医学院的Sung Ho Jang博士等应用 弥散张量纤 维束成像评估了 1例壳核岀 血患者丘脑皮质束损伤情况,并认为患者记忆障碍的主要原因是由于该神经纤维束损伤导致。
源于海马的神经通路经乳头体,丘脑前核和扣带回的中继,返回海马构成一封闭环路。以往研究应用弥散张
量纤维束成像(DTT )检测了
Papez环中的穹窿、孚[
头丘脑束和扣带。最近有研究报道了
1例患者丘脑前
Papez环最初是1937年由James Papez提岀的,其在情绪和记忆控制方面有重要作用。 Papez通路起
Papez
环的可视化和评估成为可能。
此次,Sung Ho Jang博士等首次研究了脑岀血后 Papez环变化。详细描述了 DTT如何检测丘脑皮
质束变化,以及该神经纤维束如何重建。 DTT是一种用于评估基底节损伤后 Papez环状态的有用工具。
今后,他们将进一步扩大样本量,以使研究结果更为可靠。这项结果撰写的文章发表在《中国神经再生 研究(英文版)》杂志 2015年第2期。
Article: Is thalamocortical tract injury responsible for memory impairment in a patient with putaminal hemorrhage? by
Hyeok Gyu Kwon1, Chui Hoo n Cha ng2. Sung Ho Jang1(1 Department of Physical Medicine and Rehabilitation, College of Medicine, Yeungnam University, Daegu, Republic of Korea; 2Department of Neurosurgery, College of Medicine Yeungnam University, Daegu, Republic of Korea)
Kwon HG, Chang CH, Jang SH (2015) Is thalamocortical tract injury responsible for memory impairment in a patient with putaminal hemorrhage? Neural Regen Res 10(2):321-322.
欲获更多资讯:
Neural Rege n Res
Is thalamocortical tract injury responsible for memory impairment in a patient with putaminal hemorrhage?
Dr. Sung Ho Jang, College of Medici ne, Yeu ngnam Un iversity, Republic of Korea and his colleagues evaluated the injury to the thalamocortical tract of a patie nt with putam inal hemorrhage using diffusi on ten sor tractography (DTT) and concluded that the injured thalamocortical tract between the anterior thalamic nuclei and the cingulate gyrus is a main reas on of memory impairme nt.
The Papez circuit, described by James Papez in 1937, is known to play importa nt roles in con trol of emoti on and memory. The pathway of the Papez circuit was reported as follows: hippocampal formation — fornix — mammillary bodies — anterior thalamic nuclei — cingulate gyrus — cingulum — parahippocampal gyrus — hippocampus. Previous studies using DTT have reported on injury of a portion of the Papez circuit including fornix, mammillothalam
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