血液病学溶血性贫血.ppt

;第六章 溶血性贫血;溶血性贫血（HA）概述;一、定义;二、临床分类;（一）红细胞自身异常所致的HA;红细胞膜异常;遗传性红细胞酶的缺乏;遗传性珠蛋白生成障碍;血红素异常;9、 人的价值，在招收诱惑的一瞬间被决定。*** 10、低头要有勇气，抬头要有低气。**** 11、人总是珍惜为得到。***** 12、人乱于心，不宽余请。**** 13、生气是拿别人做错的事来惩罚自己。***** 14、抱最大的希望，作最大的努力。**** 15、一个人炫耀什么，说明他内心缺少什么。。***** 16、业余生活要有意义，不要越轨。*** 17、一个人即使已登上顶峰，也仍要自强不息。****;（二）红细胞外部异常所致的HA ;免疫性HA;血管性;生物因素、理化因素;（三）临床表现;（四）发病机制和临床表现;红细胞破坏和血红蛋白降解;红细胞破坏和血红蛋白降解;血管外溶血的一种特殊形式;红系代偿性增生;红细胞具有缺陷或寿命缩短;（五）诊断和鉴别诊断;鉴别诊断;自身免疫性溶血性贫血;温抗体型AIHA;一、病因;二、临床表现;三、实验室检查;三、实验室检查;四、诊断;原发性多为女性，年龄不限。临床表现除溶血和贫血外无特殊症状，半数有脾肿大，1/3有黄疸和肝大，继发性常伴有原发病的临床表现。;实验室检查;五、治疗;冷抗体型AIHA;ANEMIAS OF EFFECTIVE ERYTHROPOIESIS;Anemias of Effective Erythropoiesis: Module Objectives;Anemias of Effective Erythropoiesis: Module Objectives;Anemias of Effective Erythropoiesis: Module Objectives;Anemias of Effective Erythropoiesis: Module Objectives;Anemias of Effective Erythropoiesis: Module Objectives;Anemias of Effective Erythropoiesis: Module Objectives;Anemias of Effective Erythropoiesis: Module Objectives;Anemias of Effective Erythropoiesis: Module Objectives;Anemias of Effective Erythropoiesis: Module Objectives;ClassificationHemolytic Anemia;Sites of HemolysisHemolytic Anemia;Sites of Hemolysis;Sites of Hemolysis;Sites of Hemolysis;Catabolism;Primary Laboratory Investigation;Primary Laboratory Investigation;;Morphology in HA;Secondary Laboratory Investigation;Secondary Laboratory Investigation;Secondary Laboratory Investigation;Secondary Laboratory Investigation;Survey of HA by Type;Hereditary HA;RBC Membrane Structure;Membrane Abnormalities;Membrane Abnormalities;;Hereditary Spherocytosis;Hereditary Spherocytosis;;Hereditary Elliptocytosis;;Hereditary Elliptocytosis;Hereditary Elliptocytosis;Hereditary Pyropoikilocytosis;Hereditary Pyropoikilocytosis;Hereditary Stomatocytosis;;Hereditary Stomatocytosis;EnzymopathiesHemolytic Anemia;EnzymopathiesHemolytic Anemia;EnzymopathiesHemolytic Anemia;;EnzymopathiesHemolytic Anemia;EnzymopathiesHemolytic Anemia;Plasma Constituent Abnormalities;;Target